| Starters | ||
| Pos | Player | Points |
| QB | Philip Rivers QB | 17.04 |
| RB | Devontae Booker RB | 9.80 |
| RB | Jordan Howard RB | 9.00 |
| WR | Odell Beckham WR | 20.70 |
| WR | Kelvin Benjamin WR | 10.90 |
| TE | Travis Kelce TE | 6.60 |
| FLEX | David Johnson RB | 24.60 |
| FLEX | Jordan Matthews TE | 10.30 |
| DST | Philadelphia Eagles DST | 5.00 |
| Total | 113.94 | |
| Starters | ||
| Pos | Player | Points |
| QB | Joe Flacco QB | 22.14 |
| RB | LeVeon Bell RB | 29.90 |
| RB | Devonta Freeman RB | 9.60 |
| WR | Doug Baldwin WR | 26.90 |
| WR | Brandon Marshall WR | 3.50 |
| TE | Zach Miller TE | 5.20 |
| FLEX | Lamar Miller RB | 8.30 |
| FLEX | Greg Olsen TE | 6.40 |
| DST | Los Angeles Rams DST | 9.00 |
| Total | 120.94 | |
| Bench | ||
| Pos | Player | Points |
| BN | Russell Wilson QB | 26.52 |
| BN | Knile Davis RB | 1.05 |
| BN | Derrick Henry RB | 3.10 |
| BN | Carlos Hyde RB | 1.40 |
| BN | Theo Riddick RB | 0.00 |
| BN | Terrance West RB | 8.20 |
| BN | Tyler Lockett WR | 10.50 |
| BN | Donte Moncrief WR | 0.00 |
| BN | Willie Snead WR | 19.20 |
| BN | Cameron Brate TE | 17.90 |
| Bench | ||
| Pos | Player | Points |
| BN | Carson Palmer QB | 14.64 |
| BN | Alex Smith QB | 8.42 |
| BN | Danny Amendola WR | 1.90 |
| BN | Ted Ginn Jr. WR | 7.45 |
| BN | Tyreek Hill WR | 16.45 |
| BN | Eddie Royal WR | 2.75 |
| BN | Martellus Bennett TE | 13.70 |
| BN | Jordan Cameron TE | 0.00 |
| BN | Cincinnati Bengals DST | 4.00 |
| BN | New England Patriots DST | 1.00 |
| BN | Houston Texans DST | 12.00 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Russell Wilson QB | 26.52 | 64.3% |
| RB | David Johnson RB | 24.60 | 54.7% |
| RB | Devontae Booker RB | 9.80 | |
| WR | Odell Beckham WR | 20.70 | 79.2% |
| WR | Willie Snead WR | 19.20 | |
| TE | Cameron Brate TE | 17.90 | 36.9% |
| FLEX | Kelvin Benjamin WR | 10.90 | 163.1% |
| FLEX | Tyler Lockett WR | 10.50 | |
| DST | Philadelphia Eagles DST | 5.00 | 100% |
| Total | 145.12 | 78.5% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Joe Flacco QB | 22.14 | 100% |
| RB | LeVeon Bell RB | 29.90 | 100% |
| RB | Devonta Freeman RB | 9.60 | |
| WR | Doug Baldwin WR | 26.90 | 70.1% |
| WR | Tyreek Hill WR | 16.45 | |
| TE | Martellus Bennett TE | 13.70 | 38% |
| FLEX | Lamar Miller RB | 8.30 | 93.3% |
| FLEX | Ted Ginn Jr. WR | 7.45 | |
| DST | Houston Texans DST | 12.00 | 75% |
| Total | 146.44 | 82.6% | |