| Starters | ||
| Pos | Player | Points |
| QB | Andrew Luck QB | 29.72 |
| RB | Kenneth Dixon RB | 9.70 |
| RB | Darren Sproles RB | 14.25 |
| WR | Will Fuller WR | 9.20 |
| WR | DeAndre Hopkins WR | 13.30 |
| TE | Eric Ebron TE | 5.80 |
| FLEX | Julio Jones WR | 14.80 |
| FLEX | Malcolm Mitchell WR | 12.20 |
| DST | Denver Broncos DST | 16.00 |
| Total | 124.97 | |
| Starters | ||
| Pos | Player | Points |
| QB | Russell Wilson QB | 15.98 |
| RB | Devontae Booker RB | 10.20 |
| RB | Jordan Howard RB | 29.70 |
| WR | Odell Beckham WR | 15.00 |
| WR | Donte Moncrief WR | 10.60 |
| TE | Travis Kelce TE | 18.00 |
| FLEX | Carlos Hyde RB | 10.30 |
| FLEX | David Johnson RB | 34.00 |
| DST | Philadelphia Eagles DST | 0.00 |
| Total | 143.78 | |
| Bench | ||
| Pos | Player | Points |
| BN | Ryan Fitzpatrick QB | 1.54 |
| BN | Marcus Mariota QB | 0.00 |
| BN | Mike Gillislee RB | 16.90 |
| BN | Paul Perkins RB | 3.80 |
| BN | T.J. Yeldon RB | 9.70 |
| BN | Marqise Lee WR | 5.90 |
| BN | Sterling Shepard WR | 10.10 |
| BN | Robert Woods WR | 0.00 |
| BN | Delanie Walker TE | 0.00 |
| BN | Pittsburgh Steelers DST | 11.00 |
| Bench | ||
| Pos | Player | Points |
| BN | Philip Rivers QB | 14.80 |
| BN | Knile Davis RB | 0.00 |
| BN | Derrick Henry RB | 0.00 |
| BN | Theo Riddick RB | 10.20 |
| BN | Terrance West RB | 20.30 |
| BN | Kelvin Benjamin WR | 2.80 |
| BN | Tyler Lockett WR | 25.20 |
| BN | Jordan Matthews TE | 0.00 |
| BN | Willie Snead WR | 4.80 |
| BN | Cameron Brate TE | 17.60 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Andrew Luck QB | 29.72 | 100% |
| RB | Mike Gillislee RB | 16.90 | 76.9% |
| RB | Darren Sproles RB | 14.25 | |
| WR | Julio Jones WR | 14.80 | 80.1% |
| WR | DeAndre Hopkins WR | 13.30 | |
| TE | Eric Ebron TE | 5.80 | 100% |
| FLEX | Malcolm Mitchell WR | 12.20 | 121.1% |
| FLEX | Sterling Shepard WR | 10.10 | |
| DST | Denver Broncos DST | 16.00 | 100% |
| Total | 133.07 | 93.9% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Russell Wilson QB | 15.98 | 100% |
| RB | David Johnson RB | 34.00 | 62.6% |
| RB | Jordan Howard RB | 29.70 | |
| WR | Tyler Lockett WR | 25.20 | 63.7% |
| WR | Odell Beckham WR | 15.00 | |
| TE | Travis Kelce TE | 18.00 | 100% |
| FLEX | Terrance West RB | 20.30 | 116.9% |
| FLEX | Cameron Brate TE | 17.60 | |
| DST | Philadelphia Eagles DST | 0.00 | -- |
| Total | 175.78 | 81.8% | |