| Starters | ||
| Pos | Player | Points |
| QB | Derek Carr QB | 20.80 |
| RB | Rob Kelley RB | 6.30 |
| RB | Latavius Murray RB | 24.00 |
| WR | Mike Evans WR | 7.30 |
| WR | Mohamed Sanu WR | 3.60 |
| TE | Dwayne Allen TE | 27.20 |
| FLEX | Jonathan Stewart RB | 4.80 |
| FLEX | Demaryius Thomas WR | 9.10 |
| DST | Seattle Seahawks DST | 9.00 |
| Total | 112.1 | |
| Starters | ||
| Pos | Player | Points |
| QB | Tyrod Taylor QB | 12.64 |
| RB | Dion Lewis RB | 5.80 |
| RB | LeSean McCoy RB | 22.60 |
| WR | Jamison Crowder WR | 12.55 |
| WR | Taylor Gabriel WR | 6.90 |
| TE | Tyler Eifert TE | 9.50 |
| FLEX | Dontrelle Inman WR | 11.90 |
| FLEX | Michael Thomas WR | 6.20 |
| Total | 88.09 | |
| Bench | ||
| Pos | Player | Points |
| BN | Blake Bortles QB | 10.14 |
| BN | Jimmy Garoppolo QB | 0.00 |
| BN | Carson Wentz QB | 12.62 |
| BN | Cameron Artis-Payne RB | 0.00 |
| BN | Isaiah Crowell RB | 0.00 |
| BN | Jeremy Langford RB | 0.20 |
| BN | DeAndre Washington RB | 0.00 |
| BN | Corey Coleman WR | 0.00 |
| BN | Allen Hurns WR | 0.00 |
| BN | Sammy Watkins WR | 5.30 |
| BN | Dallas Cowboys DST | 6.00 |
| Bench | ||
| Pos | Player | Points |
| BN | Tyler Eifert TE | 2.00 |
| BN | Jameis Winston QB | 15.30 |
| BN | Jerick McKinnon RB | 14.00 |
| BN | Christine Michael RB | 1.90 |
| BN | Alshon Jeffery WR | 0.00 |
| BN | Jeremy Maclin WR | 0.00 |
| BN | Terrelle Pryor WR | 0.00 |
| BN | Tyrell Williams WR | 11.70 |
| BN | Ladarius Green TE | 20.00 |
| BN | Jason Witten TE | 0.00 |
| BN | Chicago Bears DST | 15.00 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Derek Carr QB | 20.80 | 100% |
| RB | Latavius Murray RB | 24.00 | 100% |
| RB | Rob Kelley RB | 6.30 | |
| WR | Demaryius Thomas WR | 9.10 | 66.5% |
| WR | Mike Evans WR | 7.30 | |
| TE | Dwayne Allen TE | 27.20 | 100% |
| FLEX | Sammy Watkins WR | 5.30 | 137.6% |
| FLEX | Jonathan Stewart RB | 4.80 | |
| DST | Seattle Seahawks DST | 9.00 | 100% |
| Total | 113.8 | 98.5% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Jameis Winston QB | 15.30 | 82.6% |
| RB | LeSean McCoy RB | 22.60 | 77.6% |
| RB | Jerick McKinnon RB | 14.00 | |
| WR | Jamison Crowder WR | 12.55 | 79.6% |
| WR | Dontrelle Inman WR | 11.90 | |
| TE | Ladarius Green TE | 20.00 | 47.5% |
| FLEX | Tyrell Williams WR | 11.70 | 85.4% |
| FLEX | Tyler Eifert TE | 9.50 | |
| DST | Chicago Bears DST | 15.00 | 0% |
| Total | 132.55 | 66.5% | |