| Starters | ||
| Pos | Player | Points |
| QB | Derek Carr QB | 4.98 |
| RB | Isaiah Crowell RB | 12.30 |
| RB | Rob Kelley RB | 15.80 |
| WR | Mike Evans WR | 6.20 |
| WR | Demaryius Thomas WR | 17.60 |
| TE | Dwayne Allen TE | 0.00 |
| FLEX | Latavius Murray RB | 16.30 |
| FLEX | Jonathan Stewart RB | 12.60 |
| DST | Seattle Seahawks DST | -2.00 |
| Total | 83.78 | |
| Starters | ||
| Pos | Player | Points |
| QB | Jameis Winston QB | 8.96 |
| RB | Dion Lewis RB | 2.40 |
| RB | LeSean McCoy RB | 19.80 |
| WR | Jamison Crowder WR | 5.35 |
| WR | Taylor Gabriel WR | 15.70 |
| TE | Tyler Eifert TE | 19.30 |
| FLEX | Tyrell Williams WR | 7.80 |
| FLEX | Ladarius Green TE | 3.50 |
| Total | 82.81 | |
| Bench | ||
| Pos | Player | Points |
| BN | Blake Bortles QB | 15.58 |
| BN | Jimmy Garoppolo QB | 0.00 |
| BN | Carson Wentz QB | 13.06 |
| BN | Cameron Artis-Payne RB | 0.00 |
| BN | Jeremy Langford RB | 1.00 |
| BN | DeAndre Washington RB | 0.00 |
| BN | Corey Coleman WR | 4.20 |
| BN | Allen Hurns WR | 0.00 |
| BN | Mohamed Sanu WR | 0.00 |
| BN | Sammy Watkins WR | 13.40 |
| BN | Dallas Cowboys DST | 14.00 |
| Bench | ||
| Pos | Player | Points |
| BN | Ladarius Green TE | 5.00 |
| BN | Tyrod Taylor QB | 15.32 |
| BN | Jerick McKinnon RB | 9.90 |
| BN | Christine Michael RB | 3.60 |
| BN | Dontrelle Inman WR | 16.10 |
| BN | Alshon Jeffery WR | 0.00 |
| BN | Jeremy Maclin WR | 2.10 |
| BN | Terrelle Pryor WR | 0.80 |
| BN | Michael Thomas WR | 0.00 |
| BN | Jason Witten TE | 4.60 |
| BN | Chicago Bears DST | 13.00 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Blake Bortles QB | 15.58 | 32% |
| RB | Latavius Murray RB | 16.30 | 87.5% |
| RB | Rob Kelley RB | 15.80 | |
| WR | Demaryius Thomas WR | 17.60 | 76.8% |
| WR | Sammy Watkins WR | 13.40 | |
| TE | Dwayne Allen TE | 0.00 | -- |
| FLEX | Jonathan Stewart RB | 12.60 | 116.1% |
| FLEX | Isaiah Crowell RB | 12.30 | |
| DST | Dallas Cowboys DST | 14.00 | -14.3% |
| Total | 117.58 | 71.3% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Tyrod Taylor QB | 15.32 | 58.5% |
| RB | LeSean McCoy RB | 19.80 | 74.7% |
| RB | Jerick McKinnon RB | 9.90 | |
| WR | Dontrelle Inman WR | 16.10 | 66.2% |
| WR | Taylor Gabriel WR | 15.70 | |
| TE | Tyler Eifert TE | 19.30 | 100% |
| FLEX | Tyrell Williams WR | 7.80 | 85.9% |
| FLEX | Jamison Crowder WR | 5.35 | |
| DST | Chicago Bears DST | 13.00 | 0% |
| Total | 122.27 | 67.7% | |