| Starters | ||
| Pos | Player | Points |
| QB | Matt Ryan QB | 6.80 |
| RB | Leonard Fournette RB | 19.90 |
| RB | Duke Johnson RB | 13.20 |
| WR | DeAndre Hopkins WR | 30.40 |
| WR | Julio Jones WR | 12.30 |
| TE | Jimmy Graham TE | 0.00 |
| FLEX | Marqise Lee WR | 9.00 |
| FLEX | Devin Funchess TE | 13.40 |
| DST | Houston Texans DST | 1.00 |
| Total | 106 | |
| Starters | ||
| Pos | Player | Points |
| QB | Drew Brees QB | 17.00 |
| RB | Mark Ingram RB | 11.20 |
| RB | Rex Burkhead RB | 13.80 |
| WR | Antonio Brown WR | 26.80 |
| WR | Robby Anderson WR | 4.20 |
| TE | Delanie Walker TE | 6.70 |
| FLEX | Michael Crabtree WR | 11.50 |
| FLEX | Tevin Coleman RB | 3.20 |
| DST | Los Angeles Chargers DST | 9.00 |
| Total | 103.4 | |
| Bench | ||
| Pos | Player | Points |
| BN | Matthew Stafford QB | 15.20 |
| BN | C.J. Anderson RB | 8.30 |
| BN | Mike Williams WR | 0.80 |
| BN | Kenny Golladay WR | 4.10 |
| BN | Rob Gronkowski TE | 0.00 |
| BN | Chris Ivory RB | 4.80 |
| BN | Paul Richardson WR | 14.70 |
| BN | Patrick Mahomes QB | 0.00 |
| BN | Chicago Bears DST | 12.00 |
| BN | Jeremy Maclin WR | 4.20 |
| Bench | ||
| Pos | Player | Points |
| BN | Joe Mixon RB | 0.00 |
| BN | Jordy Nelson WR | 5.30 |
| BN | Martavis Bryant WR | 9.10 |
| BN | James Conner RB | 0.60 |
| BN | Deshaun Watson QB | 0.00 |
| BN | Terrelle Pryor WR | 0.00 |
| BN | Matt Breida RB | 2.70 |
| BN | Tennessee Titans DST | 13.00 |
| BN | Damien Williams RB | 0.00 |
| BN | Will Fuller WR | 4.10 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Matthew Stafford QB | 15.20 | 44.7% |
| RB | Leonard Fournette RB | 19.90 | 100% |
| RB | Duke Johnson RB | 13.20 | |
| WR | DeAndre Hopkins WR | 30.40 | 94.7% |
| WR | Paul Richardson WR | 14.70 | |
| TE | Devin Funchess TE | 13.40 | 0% |
| FLEX | Julio Jones WR | 12.30 | 105.2% |
| FLEX | Marqise Lee WR | 9.00 | |
| DST | Chicago Bears DST | 12.00 | 8.3% |
| Total | 140.1 | 75.7% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Drew Brees QB | 17.00 | 100% |
| RB | Rex Burkhead RB | 13.80 | 100% |
| RB | Mark Ingram RB | 11.20 | |
| WR | Antonio Brown WR | 26.80 | 80.9% |
| WR | Michael Crabtree WR | 11.50 | |
| TE | Delanie Walker TE | 6.70 | 100% |
| FLEX | Martavis Bryant WR | 9.10 | 102.1% |
| FLEX | Jordy Nelson WR | 5.30 | |
| DST | Tennessee Titans DST | 13.00 | 69.2% |
| Total | 114.4 | 90.4% | |