| Starters | ||
| Pos | Player | Points |
| QB | Patrick Mahomes QB | 38.84 |
| RB | Duke Johnson RB | 2.00 |
| RB | Phillip Lindsay RB | 11.60 |
| WR | DeAndre Hopkins WR | 20.00 |
| WR | Julio Jones WR | 8.90 |
| TE | Jordan Reed TE | 6.50 |
| FLEX | Pierre Garcon WR | 7.70 |
| FLEX | Kenny Golladay WR | 17.90 |
| DST | Chicago Bears DST | 19.00 |
| Total | 132.44 | |
| Starters | ||
| Pos | Player | Points |
| QB | Kirk Cousins QB | 33.50 |
| RB | Carlos Hyde RB | 11.50 |
| RB | Saquon Barkley RB | 17.80 |
| WR | Larry Fitzgerald WR | 4.30 |
| WR | Jarvis Landry WR | 9.40 |
| TE | George Kittle TE | 3.20 |
| FLEX | Bilal Powell RB | 16.50 |
| FLEX | Golden Tate WR | 15.30 |
| DST | Los Angeles Rams DST | 11.00 |
| Total | 122.5 | |
| Bench | ||
| Pos | Player | Points |
| BN | Sterling Shepard WR | 3.90 |
| BN | Matt Ryan QB | 30.68 |
| BN | Rishard Matthews WR | 1.80 |
| BN | Houston Texans DST | 3.00 |
| BN | Mike Wallace WR | 0.00 |
| BN | C.J. Anderson RB | 3.10 |
| BN | Leonard Fournette RB | |
| BN | Tarik Cohen RB | 5.90 |
| BN | Evan Engram TE | 16.20 |
| BN | Mike Williams WR | 9.70 |
| Bench | ||
| Pos | Player | Points |
| BN | Cameron Meredith WR | 0.00 |
| BN | Trey Burton TE | 10.20 |
| BN | Allen Hurns WR | 1.40 |
| BN | Alex Smith QB | 13.08 |
| BN | Ty Montgomery RB | 4.50 |
| BN | Nick Chubb RB | 1.40 |
| BN | Rashaad Penny RB | 3.00 |
| BN | Nyheim Hines RB | 7.00 |
| BN | Courtland Sutton WR | 1.40 |
| BN | Christian Kirk WR | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Patrick Mahomes QB | 38.84 | 100% |
| RB | Phillip Lindsay RB | 11.60 | 62.4% |
| RB | Chris Ivory RB | 10.20 | |
| WR | DeAndre Hopkins WR | 20.00 | 76.3% |
| WR | Kenny Golladay WR | 17.90 | |
| TE | Evan Engram TE | 16.20 | 40.1% |
| FLEX | Will Dissly TE | 11.70 | 119.6% |
| FLEX | Mike Williams WR | 9.70 | |
| DST | Chicago Bears DST | 19.00 | 100% |
| Total | 155.14 | 85.4% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Kirk Cousins QB | 33.50 | 100% |
| RB | Saquon Barkley RB | 17.80 | 85.4% |
| RB | Bilal Powell RB | 16.50 | |
| WR | Golden Tate WR | 15.30 | 55.5% |
| WR | Jarvis Landry WR | 9.40 | |
| TE | Trey Burton TE | 10.20 | 31.4% |
| FLEX | Carlos Hyde RB | 11.50 | 160.6% |
| FLEX | Jakeem Grant WR | 8.30 | |
| DST | Los Angeles Rams DST | 11.00 | 100% |
| Total | 133.5 | 91.8% | |