| Starters | ||
| Pos | Player | Points |
| QB | Drew Brees QB | 40.50 |
| RB | Todd Gurley RB | 22.10 |
| RB | Chris Thompson RB | 2.20 |
| WR | Stefon Diggs WR | 3.70 |
| WR | Keenan Allen WR | 3.90 |
| TE | Rob Gronkowski TE | 7.10 |
| FLEX | Josh Doctson WR | 0.00 |
| FLEX | Cooper Kupp WR | 14.80 |
| DST | New Orleans Saints DST | -1.00 |
| Total | 93.3 | |
| Starters | ||
| Pos | Player | Points |
| QB | Russell Wilson QB | 15.60 |
| RB | Alvin Kamara RB | 27.30 |
| RB | Kareem Hunt RB | 16.40 |
| WR | A.J. Green WR | 8.30 |
| WR | JuJu Smith-Schuster WR | 16.10 |
| TE | Jimmy Graham TE | 7.00 |
| FLEX | DeSean Jackson WR | 5.20 |
| FLEX | Alex Collins RB | 14.90 |
| DST | Philadelphia Eagles DST | 5.00 |
| Total | 115.8 | |
| Bench | ||
| Pos | Player | Points |
| BN | Tavon Austin WR | 10.50 |
| BN | Hunter Henry TE | 0.00 |
| BN | Atlanta Falcons DST | -8.00 |
| BN | John Brown WR | 11.10 |
| BN | LeGarrette Blount RB | 7.50 |
| BN | Doug Martin RB | 4.30 |
| BN | Josh Rosen QB | 0.60 |
| BN | Sam Darnold QB | 2.80 |
| BN | Ronald Jones II RB | 0.00 |
| BN | JMon Moore WR | 0.00 |
| Bench | ||
| Pos | Player | Points |
| BN | Tyler Boyd WR | 22.70 |
| BN | Tyrod Taylor QB | 3.00 |
| BN | Devin Funchess TE | 14.70 |
| BN | Doug Baldwin WR | 0.00 |
| BN | Javorius Allen RB | 16.10 |
| BN | Charles Clay TE | 2.80 |
| BN | Jared Goff QB | 25.60 |
| BN | Kerryon Johnson RB | 12.00 |
| BN | Jordan Wilkins RB | 3.00 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Drew Brees QB | 40.50 | 100% |
| RB | Todd Gurley RB | 22.10 | 82.1% |
| RB | LeGarrette Blount RB | 7.50 | |
| WR | Cooper Kupp WR | 14.80 | 29.3% |
| WR | John Brown WR | 11.10 | |
| TE | Rob Gronkowski TE | 7.10 | 100% |
| FLEX | Tavon Austin WR | 10.50 | 100% |
| FLEX | Doug Martin RB | 4.30 | |
| DST | New Orleans Saints DST | -1.00 | -- |
| Total | 116.9 | 79.8% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Jared Goff QB | 25.60 | 60.9% |
| RB | Alvin Kamara RB | 27.30 | 100% |
| RB | Kareem Hunt RB | 16.40 | |
| WR | Tyler Boyd WR | 22.70 | 62.9% |
| WR | JuJu Smith-Schuster WR | 16.10 | |
| TE | Devin Funchess TE | 14.70 | 47.6% |
| FLEX | Javorius Allen RB | 16.10 | 64.8% |
| FLEX | Alex Collins RB | 14.90 | |
| DST | Philadelphia Eagles DST | 5.00 | 100% |
| Total | 158.8 | 72.9% | |