| Starters | ||
| Pos | Player | Points |
| QB | Carson Wentz QB | 11.20 |
| RB | Adrian Peterson RB | 24.00 |
| RB | Royce Freeman RB | 12.30 |
| WR | Allen Robinson WR | 6.50 |
| WR | Mike Evans WR | 22.70 |
| TE | David Njoku TE | 4.60 |
| FLEX | Quincy Enunwa WR | 7.70 |
| FLEX | Demaryius Thomas WR | 8.80 |
| DST | Seattle Seahawks DST | 14.00 |
| Total | 111.8 | |
| Starters | ||
| Pos | Player | Points |
| QB | Tom Brady QB | 7.50 |
| RB | Ezekiel Elliott RB | 13.30 |
| RB | Melvin Gordon RB | 15.40 |
| WR | Robert Woods WR | 28.70 |
| WR | Antonio Brown WR | 14.00 |
| TE | Ricky Seals-Jones TE | 10.00 |
| FLEX | Sammy Watkins WR | 16.00 |
| FLEX | Matt Breida RB | 13.20 |
| DST | Minnesota Vikings DST | 5.00 |
| Total | 123.1 | |
| Bench | ||
| Pos | Player | Points |
| BN | Andy Dalton QB | 14.10 |
| BN | Jalen Richard RB | 8.90 |
| BN | Rob Kelley RB | 0.00 |
| BN | Mohamed Sanu WR | 13.60 |
| BN | Jesse James TE | 1.20 |
| BN | Dez Bryant WR | 0.00 |
| BN | Frank Gore RB | 1.20 |
| BN | Dalvin Cook RB | 0.00 |
| BN | John Ross WR | 3.10 |
| BN | Keelan Cole WR | 6.50 |
| Bench | ||
| Pos | Player | Points |
| BN | Jacksonville Jaguars DST | 8.00 |
| BN | Michael Crabtree WR | 9.60 |
| BN | Rex Burkhead RB | 3.60 |
| BN | Brandon Marshall WR | 4.00 |
| BN | Phillip Dorsett WR | 0.00 |
| BN | Marquise Goodwin WR | 10.30 |
| BN | Corey Grant RB | 1.50 |
| BN | Ryan Grant WR | 11.00 |
| BN | Albert Wilson WR | 20.50 |
| BN | Vance McDonald TE | 19.20 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Andy Dalton QB | 14.10 | 79.4% |
| RB | Adrian Peterson RB | 24.00 | 100% |
| RB | Royce Freeman RB | 12.30 | |
| WR | Mike Evans WR | 22.70 | 80.4% |
| WR | Mohamed Sanu WR | 13.60 | |
| TE | Mike Gesicki TE | 4.60 | 100% |
| FLEX | Jalen Richard RB | 8.90 | 93.2% |
| FLEX | Demaryius Thomas WR | 8.80 | |
| DST | Seattle Seahawks DST | 14.00 | 100% |
| Total | 123 | 90.9% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Eli Manning QB | 19.80 | 37.9% |
| RB | Melvin Gordon RB | 15.40 | 100% |
| RB | Ezekiel Elliott RB | 13.30 | |
| WR | Robert Woods WR | 28.70 | 86.8% |
| WR | Albert Wilson WR | 20.50 | |
| TE | Vance McDonald TE | 19.20 | 52.1% |
| FLEX | Sammy Watkins WR | 16.00 | 97.3% |
| FLEX | Antonio Brown WR | 14.00 | |
| DST | Jacksonville Jaguars DST | 8.00 | 62.5% |
| Total | 154.9 | 79.5% | |