| Starters | ||
| Pos | Player | Points |
| QB | Matthew Stafford QB | 10.10 |
| RB | C.J. Anderson RB | 13.20 |
| RB | Leonard Fournette RB | 22.50 |
| WR | DeAndre Hopkins WR | 21.70 |
| WR | DeVante Parker WR | 9.90 |
| TE | Rob Gronkowski TE | 10.00 |
| FLEX | Marqise Lee WR | 2.80 |
| FLEX | Paul Richardson WR | 8.00 |
| DST | Houston Texans DST | 22.00 |
| Total | 120.2 | |
| Starters | ||
| Pos | Player | Points |
| QB | Drew Brees QB | 19.00 |
| RB | Mark Ingram RB | 8.20 |
| RB | LeSean McCoy RB | 12.30 |
| WR | Antonio Brown WR | 6.20 |
| WR | Jordy Nelson WR | 21.50 |
| TE | Delanie Walker TE | 6.60 |
| FLEX | Joe Mixon RB | 6.80 |
| FLEX | Chris Carson RB | 8.10 |
| DST | Green Bay Packers DST | 10.00 |
| Total | 98.7 | |
| Bench | ||
| Pos | Player | Points |
| BN | Paul Perkins RB | 2.40 |
| BN | Randall Cobb WR | 12.40 |
| BN | Eric Decker WR | 2.30 |
| BN | Mike Williams WR | 0.00 |
| BN | Kenny Golladay WR | 0.00 |
| BN | Devin Funchess TE | 22.50 |
| BN | Mike Tolbert RB | 3.10 |
| BN | Duke Johnson RB | 16.50 |
| BN | Rashard Higgins WR | 0.00 |
| BN | Chicago Bears DST | 1.00 |
| Bench | ||
| Pos | Player | Points |
| BN | Wendell Smallwood RB | 15.90 |
| BN | Michael Crabtree WR | 0.00 |
| BN | Martavis Bryant WR | 6.30 |
| BN | Robby Anderson WR | 7.40 |
| BN | James Conner RB | 2.60 |
| BN | Deshaun Watson QB | 33.70 |
| BN | Terrance Williams WR | 5.40 |
| BN | Terrelle Pryor WR | 14.50 |
| BN | Benjamin Watson TE | 6.80 |
| BN | Eli Manning QB | 27.70 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Matthew Stafford QB | 10.10 | 100% |
| RB | Leonard Fournette RB | 22.50 | 91.5% |
| RB | Duke Johnson RB | 16.50 | |
| WR | DeAndre Hopkins WR | 21.70 | 92.7% |
| WR | Randall Cobb WR | 12.40 | |
| TE | Devin Funchess TE | 22.50 | 44.4% |
| FLEX | C.J. Anderson RB | 13.20 | 46.6% |
| FLEX | Rob Gronkowski TE | 10.00 | |
| DST | Houston Texans DST | 22.00 | 100% |
| Total | 150.9 | 79.7% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Deshaun Watson QB | 33.70 | 56.4% |
| RB | Wendell Smallwood RB | 15.90 | 72.7% |
| RB | LeSean McCoy RB | 12.30 | |
| WR | Jordy Nelson WR | 21.50 | 76.9% |
| WR | Terrelle Pryor WR | 14.50 | |
| TE | Benjamin Watson TE | 6.80 | 97.1% |
| FLEX | Mark Ingram RB | 8.20 | 91.4% |
| FLEX | Chris Carson RB | 8.10 | |
| DST | Green Bay Packers DST | 10.00 | 100% |
| Total | 131 | 75.3% | |