| Starters | ||
| Pos | Player | Points |
| QB | Carson Wentz QB | 21.00 |
| RB | Frank Gore RB | 6.30 |
| RB | Royce Freeman RB | 6.20 |
| WR | Quincy Enunwa WR | 0.00 |
| WR | Keelan Cole WR | 9.00 |
| TE | David Njoku TE | 9.90 |
| FLEX | Demaryius Thomas WR | 19.00 |
| FLEX | Adrian Peterson RB | 5.20 |
| DST | Seattle Seahawks DST | -1.00 |
| Total | 75.6 | |
| Starters | ||
| Pos | Player | Points |
| QB | Andrew Luck QB | 22.60 |
| RB | Isaiah Crowell RB | 29.60 |
| RB | Marshawn Lynch RB | 5.10 |
| WR | Michael Thomas WR | 9.40 |
| WR | Corey Davis WR | 6.90 |
| TE | Austin Seferian-Jenkins TE | 0.00 |
| FLEX | Jamison Crowder WR | 7.50 |
| FLEX | Alshon Jeffery WR | 4.90 |
| DST | Tennessee Titans DST | 8.00 |
| Total | 94 | |
| Bench | ||
| Pos | Player | Points |
| BN | Andy Dalton QB | 12.90 |
| BN | Jalen Richard RB | 8.70 |
| BN | Allen Robinson WR | 0.00 |
| BN | Mike Evans WR | 0.00 |
| BN | Mohamed Sanu WR | 15.30 |
| BN | Jesse James TE | 3.00 |
| BN | Dez Bryant WR | 0.00 |
| BN | Dalvin Cook RB | 0.00 |
| BN | John Ross WR | 0.00 |
| BN | Las Vegas Raiders DST | -2.00 |
| Bench | ||
| Pos | Player | Points |
| BN | Denver Broncos DST | -2.00 |
| BN | Peyton Barber RB | 0.00 |
| BN | Josh Gordon WR | 12.00 |
| BN | Jameis Winston QB | 0.00 |
| BN | Tyler Eifert TE | 0.00 |
| BN | Ed Dickson TE | 0.00 |
| BN | Mitch Trubisky QB | 0.00 |
| BN | Marlon Mack RB | 0.00 |
| BN | Ito Smith RB | 7.50 |
| BN | Marquez Valdes-Scantling WR | 16.30 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Carson Wentz QB | 21.00 | 100% |
| RB | Jalen Richard RB | 8.70 | 83.3% |
| RB | Frank Gore RB | 6.30 | |
| WR | Demaryius Thomas WR | 19.00 | 26.2% |
| WR | Mohamed Sanu WR | 15.30 | |
| TE | David Njoku TE | 9.90 | 100% |
| FLEX | Keelan Cole WR | 9.00 | 159.2% |
| FLEX | Royce Freeman RB | 6.20 | |
| DST | Seattle Seahawks DST | -1.00 | -- |
| Total | 94.4 | 80.1% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Andrew Luck QB | 22.60 | 100% |
| RB | Isaiah Crowell RB | 29.60 | 93.5% |
| RB | Ito Smith RB | 7.50 | |
| WR | Marquez Valdes-Scantling WR | 16.30 | 57.6% |
| WR | Josh Gordon WR | 12.00 | |
| TE | Ed Dickson TE | 0.00 | -- |
| FLEX | Michael Thomas WR | 9.40 | 73.4% |
| FLEX | Jamison Crowder WR | 7.50 | |
| DST | Tennessee Titans DST | 8.00 | 100% |
| Total | 112.9 | 83.3% | |