| Starters | ||
| Pos | Player | Points |
| QB | Kirk Cousins QB | 14.10 |
| RB | Carlos Hyde RB | 8.70 |
| RB | Saquon Barkley RB | 26.90 |
| WR | Jarvis Landry WR | 9.40 |
| WR | Golden Tate WR | 6.70 |
| TE | George Kittle TE | 10.80 |
| FLEX | Bilal Powell RB | 7.90 |
| FLEX | Nyheim Hines RB | 12.50 |
| DST | Los Angeles Rams DST | 0.00 |
| Total | 97 | |
| Starters | ||
| Pos | Player | Points |
| QB | Ben Roethlisberger QB | 21.60 |
| RB | Mark Ingram RB | 20.30 |
| RB | Joe Mixon RB | 19.00 |
| WR | Julian Edelman WR | 10.20 |
| WR | Calvin Ridley WR | 5.80 |
| TE | Eric Ebron TE | 27.00 |
| FLEX | Will Fuller WR | 2.50 |
| FLEX | Amari Cooper WR | 1.50 |
| DST | Cleveland Browns DST | 8.00 |
| Total | 115.9 | |
| Bench | ||
| Pos | Player | Points |
| BN | Cameron Meredith WR | 7.60 |
| BN | Trey Burton TE | 0.00 |
| BN | Alex Smith QB | 13.70 |
| BN | Ty Montgomery RB | 5.75 |
| BN | Larry Fitzgerald WR | 4.50 |
| BN | Tyler Kroft TE | 0.00 |
| BN | Nick Chubb RB | 0.20 |
| BN | Rashaad Penny RB | 0.00 |
| BN | Courtland Sutton WR | 8.80 |
| BN | Christian Kirk WR | 16.50 |
| Bench | ||
| Pos | Player | Points |
| BN | Giovani Bernard RB | 0.00 |
| BN | Tevin Coleman RB | 4.00 |
| BN | Kyle Rudolph TE | 6.60 |
| BN | LeSean McCoy RB | 11.80 |
| BN | Los Angeles Chargers DST | 12.00 |
| BN | Deshaun Watson QB | 21.00 |
| BN | Corey Clement RB | 0.00 |
| BN | Chris Godwin WR | 0.00 |
| BN | Chris Carson RB | 13.20 |
| BN | D.J. Moore WR | 8.70 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Kirk Cousins QB | 14.10 | 100% |
| RB | Saquon Barkley RB | 26.90 | 90.4% |
| RB | Nyheim Hines RB | 12.50 | |
| WR | Jakeem Grant WR | 20.70 | 43.3% |
| WR | Christian Kirk WR | 16.50 | |
| TE | George Kittle TE | 10.80 | 100% |
| FLEX | Jarvis Landry WR | 9.40 | 112.1% |
| FLEX | Courtland Sutton WR | 8.80 | |
| DST | Los Angeles Rams DST | 0.00 | -- |
| Total | 119.7 | 81% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Ben Roethlisberger QB | 21.60 | 100% |
| RB | Mark Ingram RB | 20.30 | 100% |
| RB | Joe Mixon RB | 19.00 | |
| WR | Robby Anderson WR | 25.80 | 44.4% |
| WR | Julian Edelman WR | 10.20 | |
| TE | Eric Ebron TE | 27.00 | 100% |
| FLEX | Chris Carson RB | 13.20 | 16% |
| FLEX | LeSean McCoy RB | 11.80 | |
| DST | Los Angeles Chargers DST | 12.00 | 66.7% |
| Total | 160.9 | 72% | |