| Starters | ||
| Pos | Player | Points |
| QB | Philip Rivers QB | 17.70 |
| RB | Carlos Hyde RB | 10.70 |
| RB | David Johnson RB | 10.00 |
| WR | Tyler Lockett WR | 6.20 |
| WR | Jordan Matthews WR | 7.10 |
| TE | Travis Kelce TE | 6.90 |
| FLEX | Terrance West RB | 14.00 |
| FLEX | Jordan Howard RB | 14.10 |
| DST | Los Angeles Rams DST | 29.00 |
| Total | 115.7 | |
| Starters | ||
| Pos | Player | Points |
| QB | Andy Dalton QB | -3.00 |
| RB | Danny Woodhead RB | 5.20 |
| RB | Ameer Abdullah RB | 5.60 |
| WR | Michael Thomas WR | 7.00 |
| WR | Alshon Jeffery WR | 7.30 |
| TE | Tyler Eifert TE | 0.90 |
| FLEX | Jamison Crowder WR | 1.10 |
| FLEX | Jeremy Maclin WR | 12.60 |
| DST | Carolina Panthers DST | 14.00 |
| Total | 50.7 | |
| Bench | ||
| Pos | Player | Points |
| BN | Jay Cutler QB | 0.00 |
| BN | DeAngelo Henderson RB | 0.00 |
| BN | Philadelphia Eagles DST | 23.00 |
| BN | Cameron Brate TE | 0.00 |
| BN | Willie Snead WR | 0.00 |
| BN | Donte Moncrief WR | 5.50 |
| BN | Odell Beckham WR | 0.00 |
| BN | Devontae Booker RB | 0.00 |
| BN | Theo Riddick RB | 11.60 |
| BN | Derrick Henry RB | 2.50 |
| Bench | ||
| Pos | Player | Points |
| BN | Matt Breida RB | 1.10 |
| BN | Chris Godwin WR | 0.00 |
| BN | Denver Broncos DST | 7.00 |
| BN | Eric Ebron TE | 1.90 |
| BN | Zay Jones WR | 2.60 |
| BN | Corey Davis WR | 9.90 |
| BN | Jacquizz Rodgers RB | 0.00 |
| BN | Rex Burkhead RB | 2.80 |
| BN | Marlon Mack RB | 11.00 |
| BN | Jameis Winston QB | 0.00 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Philip Rivers QB | 17.70 | 100% |
| RB | Jordan Howard RB | 14.10 | 73.7% |
| RB | Terrance West RB | 14.00 | |
| WR | Tyler Lockett WR | 6.20 | 113.7% |
| WR | Donte Moncrief WR | 5.50 | |
| TE | Jordan Matthews TE | 7.10 | 97.2% |
| FLEX | Theo Riddick RB | 11.60 | 126% |
| FLEX | Carlos Hyde RB | 10.70 | |
| DST | Los Angeles Rams DST | 29.00 | 100% |
| Total | 115.9 | 99.8% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Jameis Winston QB | 0.00 | 0% |
| RB | Marlon Mack RB | 11.00 | 65.1% |
| RB | Ameer Abdullah RB | 5.60 | |
| WR | Jeremy Maclin WR | 12.60 | 63.6% |
| WR | Corey Davis WR | 9.90 | |
| TE | Eric Ebron TE | 1.90 | 47.4% |
| FLEX | Alshon Jeffery WR | 7.30 | 95.8% |
| FLEX | Michael Thomas WR | 7.00 | |
| DST | Carolina Panthers DST | 14.00 | 100% |
| Total | 69.3 | 73.2% | |