| Starters | ||
| Pos | Player | Points |
| QB | Jameis Winston QB | 20.10 |
| RB | Marlon Mack RB | 30.90 |
| RB | Ito Smith RB | 5.50 |
| WR | Alshon Jeffery WR | 18.30 |
| WR | Michael Thomas WR | 16.40 |
| TE | C.J. Uzomah TE | 8.30 |
| FLEX | Josh Gordon WR | 12.00 |
| FLEX | Corey Davis WR | 2.50 |
| DST | Indianapolis Colts DST | 16.00 |
| Total | 130 | |
| Starters | ||
| Pos | Player | Points |
| QB | Tom Brady QB | 21.70 |
| RB | Ezekiel Elliott RB | 5.20 |
| RB | Matt Breida RB | -0.50 |
| WR | Robert Woods WR | 10.90 |
| WR | Michael Crabtree WR | 9.10 |
| TE | Ricky Seals-Jones TE | 2.20 |
| FLEX | Wendell Smallwood RB | 4.70 |
| FLEX | Sammy Watkins WR | 9.40 |
| DST | Jacksonville Jaguars DST | 3.00 |
| Total | 65.7 | |
| Bench | ||
| Pos | Player | Points |
| BN | Andrew Luck QB | 22.70 |
| BN | Peyton Barber RB | 3.00 |
| BN | Jamison Crowder WR | 0.00 |
| BN | Ed Dickson TE | 0.00 |
| BN | Marshawn Lynch RB | 0.00 |
| BN | Mitch Trubisky QB | 31.40 |
| BN | Tennessee Titans DST | 2.00 |
| BN | Derrius Guice RB | 0.00 |
| BN | Hayden Hurst TE | 0.00 |
| BN | Marquez Valdes-Scantling WR | 0.00 |
| Bench | ||
| Pos | Player | Points |
| BN | Antonio Brown WR | 0.00 |
| BN | Eli Manning QB | 20.70 |
| BN | Melvin Gordon RB | 0.00 |
| BN | Minnesota Vikings DST | 14.00 |
| BN | Marquise Goodwin WR | 3.40 |
| BN | Ryan Grant WR | 0.00 |
| BN | Albert Wilson WR | 5.10 |
| BN | Chester Rogers WR | 6.00 |
| BN | Vance McDonald TE | 0.00 |
| BN | Josh Adams RB | 1.70 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Mitch Trubisky QB | 31.40 | 64% |
| RB | Marlon Mack RB | 30.90 | 100% |
| RB | Isaiah Crowell RB | 5.50 | |
| WR | Alshon Jeffery WR | 18.30 | 100% |
| WR | Michael Thomas WR | 16.40 | |
| TE | C.J. Uzomah TE | 8.30 | 100% |
| FLEX | Josh Gordon WR | 12.00 | 82.9% |
| FLEX | Ito Smith RB | 5.50 | |
| DST | Indianapolis Colts DST | 16.00 | 100% |
| Total | 144.3 | 90.1% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Tom Brady QB | 21.70 | 100% |
| RB | Ezekiel Elliott RB | 5.20 | 47.5% |
| RB | Wendell Smallwood RB | 4.70 | |
| WR | Curtis Samuel WR | 11.55 | 89.1% |
| WR | Robert Woods WR | 10.90 | |
| TE | Ricky Seals-Jones TE | 2.20 | 100% |
| FLEX | Sammy Watkins WR | 9.40 | 76.2% |
| FLEX | Michael Crabtree WR | 9.10 | |
| DST | Minnesota Vikings DST | 14.00 | 21.4% |
| Total | 88.75 | 74% | |