| Starters | ||
| Pos | Player | Points |
| QB | Russell Wilson QB | 27.60 |
| RB | Tarik Cohen RB | 7.20 |
| RB | Kareem Hunt RB | 14.10 |
| WR | Sterling Shepard WR | 7.90 |
| WR | A.J. Green WR | 14.80 |
| TE | Jordan Reed TE | 3.60 |
| FLEX | Doug Baldwin WR | 7.00 |
| FLEX | Alvin Kamara RB | 21.80 |
| DST | Atlanta Falcons DST | 6.00 |
| Total | 110 | |
| Starters | ||
| Pos | Player | Points |
| QB | Cam Newton QB | 33.00 |
| RB | Mike Gillislee RB | 4.90 |
| RB | Todd Gurley RB | 31.00 |
| WR | Stefon Diggs WR | 12.30 |
| WR | Keenan Allen WR | 16.30 |
| TE | Hunter Henry TE | 8.60 |
| FLEX | Davante Adams WR | 8.30 |
| FLEX | Cooper Kupp WR | 14.50 |
| DST | New York Giants DST | -2.00 |
| Total | 126.9 | |
| Bench | ||
| Pos | Player | Points |
| BN | Julius Thomas TE | 3.90 |
| BN | Thomas Rawls RB | 0.00 |
| BN | Giovani Bernard RB | 15.80 |
| BN | Tyrod Taylor QB | 12.50 |
| BN | Adrian Peterson RB | 0.40 |
| BN | Charles Clay TE | 13.70 |
| BN | Bennie Fowler WR | 4.50 |
| BN | Jared Goff QB | 18.10 |
| BN | Jermaine Kearse WR | 3.70 |
| BN | Branden Oliver RB | 0.80 |
| Bench | ||
| Pos | Player | Points |
| BN | Jeremy Hill RB | 3.10 |
| BN | C.J. Prosise RB | 0.00 |
| BN | Jalen Richard RB | 3.60 |
| BN | Jared Cook TE | 6.10 |
| BN | Sam Bradford QB | 0.00 |
| BN | Nelson Agholor WR | 7.30 |
| BN | Josh Doctson WR | 3.70 |
| BN | Chris Conley WR | 4.10 |
| BN | Orleans Darkwa RB | 0.00 |
| BN | Gerald Everett TE | 1.30 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Russell Wilson QB | 27.60 | 100% |
| RB | Alvin Kamara RB | 21.80 | 56.6% |
| RB | Giovani Bernard RB | 15.80 | |
| WR | A.J. Green WR | 14.80 | 100% |
| WR | Sterling Shepard WR | 7.90 | |
| TE | Charles Clay TE | 13.70 | 26.3% |
| FLEX | Kareem Hunt RB | 14.10 | 135.2% |
| FLEX | Tarik Cohen RB | 7.20 | |
| DST | Atlanta Falcons DST | 6.00 | 100% |
| Total | 128.9 | 85.3% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Cam Newton QB | 33.00 | 100% |
| RB | Todd Gurley RB | 31.00 | 100% |
| RB | Mike Gillislee RB | 4.90 | |
| WR | Keenan Allen WR | 16.30 | 92.9% |
| WR | Cooper Kupp WR | 14.50 | |
| TE | Hunter Henry TE | 8.60 | 100% |
| FLEX | Stefon Diggs WR | 12.30 | 110.7% |
| FLEX | Davante Adams WR | 8.30 | |
| DST | New York Giants DST | -2.00 | -- |
| Total | 126.9 | 100% | |