| Starters | ||
| Pos | Player | Points |
| QB | Cam Newton QB | 21.20 |
| RB | James White RB | 25.30 |
| RB | Austin Ekeler RB | 3.90 |
| WR | Tyler Lockett WR | 5.60 |
| WR | Taylor Gabriel WR | 6.00 |
| TE | Travis Kelce TE | 25.40 |
| FLEX | Willie Snead WR | 9.30 |
| FLEX | Anthony Miller WR | 8.30 |
| DST | Carolina Panthers DST | 6.00 |
| Total | 111 | |
| Starters | ||
| Pos | Player | Points |
| QB | Deshaun Watson QB | 20.30 |
| RB | Mark Ingram RB | 2.10 |
| RB | Tevin Coleman RB | 30.10 |
| WR | Julian Edelman WR | 14.40 |
| WR | D.J. Moore WR | 5.30 |
| TE | Kyle Rudolph TE | 3.80 |
| FLEX | Chris Godwin WR | 5.00 |
| FLEX | Chris Carson RB | 4.00 |
| DST | Dallas Cowboys DST | 7.00 |
| Total | 92 | |
| Bench | ||
| Pos | Player | Points |
| BN | Philip Rivers QB | 17.10 |
| BN | Derrick Henry RB | 10.20 |
| BN | David Johnson RB | 0.00 |
| BN | Theo Riddick RB | 7.10 |
| BN | Odell Beckham WR | 0.00 |
| BN | Donte Moncrief WR | 0.00 |
| BN | Cameron Brate TE | 3.00 |
| BN | Rob Gronkowski TE | 0.00 |
| BN | Green Bay Packers DST | -2.00 |
| BN | Dallas Goedert TE | 0.00 |
| Bench | ||
| Pos | Player | Points |
| BN | Eric Ebron TE | 0.00 |
| BN | Giovani Bernard RB | 0.00 |
| BN | Amari Cooper WR | 14.30 |
| BN | LeSean McCoy RB | 4.90 |
| BN | Los Angeles Chargers DST | 12.00 |
| BN | Ben Roethlisberger QB | 25.20 |
| BN | Kansas City Chiefs DST | 5.00 |
| BN | Corey Clement RB | 0.00 |
| BN | Joe Mixon RB | 0.00 |
| BN | Calvin Ridley WR | 16.70 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Cam Newton QB | 21.20 | 100% |
| RB | James White RB | 25.30 | 82.3% |
| RB | Derrick Henry RB | 10.20 | |
| WR | Adam Humphries WR | 25.65 | 33.2% |
| WR | Willie Snead WR | 9.30 | |
| TE | Travis Kelce TE | 25.40 | 100% |
| FLEX | Spencer Ware RB | 10.10 | 95.7% |
| FLEX | Anthony Miller WR | 8.30 | |
| DST | Carolina Panthers DST | 6.00 | 100% |
| Total | 141.45 | 78.5% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Ben Roethlisberger QB | 25.20 | 80.6% |
| RB | Tevin Coleman RB | 30.10 | 92% |
| RB | LeSean McCoy RB | 4.90 | |
| WR | Calvin Ridley WR | 16.70 | 63.3% |
| WR | Julian Edelman WR | 14.40 | |
| TE | Kyle Rudolph TE | 3.80 | 100% |
| FLEX | Amari Cooper WR | 14.30 | 43.1% |
| FLEX | Michael Gallup WR | 6.60 | |
| DST | Los Angeles Chargers DST | 12.00 | 58.3% |
| Total | 128 | 71.9% | |