| Starters | ||
| Pos | Player | Points |
| QB | Matthew Stafford QB | 6.60 |
| RB | Alfred Morris RB | 1.30 |
| RB | Latavius Murray RB | 11.20 |
| WR | Jordy Nelson WR | 2.60 |
| WR | Antonio Callaway WR | 6.60 |
| TE | Greg Olsen TE | 16.60 |
| FLEX | Randall Cobb WR | 4.90 |
| FLEX | O.J. Howard TE | 19.30 |
| DST | Pittsburgh Steelers DST | 5.00 |
| Total | 74.1 | |
| Starters | ||
| Pos | Player | Points |
| QB | Mitch Trubisky QB | 8.00 |
| RB | Peyton Barber RB | 5.00 |
| RB | Isaiah Crowell RB | 6.50 |
| WR | Josh Gordon WR | 21.50 |
| WR | Michael Thomas WR | 33.10 |
| TE | Hayden Hurst TE | 2.60 |
| FLEX | Ito Smith RB | 12.90 |
| FLEX | Marquez Valdes-Scantling WR | 11.60 |
| DST | Tennessee Titans DST | 12.00 |
| Total | 113.2 | |
| Bench | ||
| Pos | Player | Points |
| BN | Arizona Cardinals DST | 0.00 |
| BN | Kelvin Benjamin WR | 6.00 |
| BN | Nelson Agholor WR | 0.00 |
| BN | Tyrell Williams WR | 9.30 |
| BN | Blake Bortles QB | 0.00 |
| BN | Chris Hogan WR | 0.00 |
| BN | Paul Richardson WR | 2.60 |
| BN | Baker Mayfield QB | 17.90 |
| BN | Ian Thomas TE | 0.00 |
| BN | TreQuan Smith WR | 9.30 |
| Bench | ||
| Pos | Player | Points |
| BN | Andrew Luck QB | 0.00 |
| BN | Jamison Crowder WR | 0.00 |
| BN | Alshon Jeffery WR | 0.00 |
| BN | Washington Commanders DST | -4.00 |
| BN | Indianapolis Colts DST | 0.00 |
| BN | Ed Dickson TE | 0.00 |
| BN | Marlon Mack RB | 0.00 |
| BN | Corey Davis WR | 9.00 |
| BN | C.J. Uzomah TE | 0.00 |
| BN | Derrius Guice RB | 0.00 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Marcus Mariota QB | 22.80 | 28.9% |
| RB | Latavius Murray RB | 11.20 | 100% |
| RB | Alfred Morris RB | 1.30 | |
| WR | TreQuan Smith WR | 9.30 | 49.5% |
| WR | Tyrell Williams WR | 9.30 | |
| TE | O.J. Howard TE | 19.30 | 86% |
| FLEX | Greg Olsen TE | 16.60 | 104.3% |
| FLEX | Antonio Callaway WR | 6.60 | |
| DST | Pittsburgh Steelers DST | 5.00 | 100% |
| Total | 101.4 | 73.1% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Mitch Trubisky QB | 8.00 | 100% |
| RB | Ito Smith RB | 12.90 | 59.3% |
| RB | Isaiah Crowell RB | 6.50 | |
| WR | Michael Thomas WR | 33.10 | 100% |
| WR | Josh Gordon WR | 21.50 | |
| TE | Hayden Hurst TE | 2.60 | 100% |
| FLEX | Marquez Valdes-Scantling WR | 11.60 | 118.9% |
| FLEX | Corey Davis WR | 9.00 | |
| DST | Tennessee Titans DST | 12.00 | 100% |
| Total | 117.2 | 96.6% | |