| Starters | ||
| Pos | Player | Points |
| QB | Jared Goff QB | 21.00 |
| RB | Alvin Kamara RB | 24.30 |
| RB | Kareem Hunt RB | 10.60 |
| WR | Devin Funchess WR | 4.70 |
| WR | JuJu Smith-Schuster WR | 17.80 |
| TE | Jimmy Graham TE | 1.80 |
| FLEX | Tyler Boyd WR | 8.00 |
| FLEX | Kerryon Johnson RB | 21.90 |
| DST | Philadelphia Eagles DST | 1.00 |
| Total | 111.1 | |
| Starters | ||
| Pos | Player | Points |
| QB | Ryan Fitzpatrick QB | 13.70 |
| RB | Frank Gore RB | 11.20 |
| RB | Adrian Peterson RB | 7.90 |
| WR | Allen Robinson WR | 28.30 |
| WR | Mike Evans WR | 6.60 |
| TE | David Njoku TE | 2.30 |
| FLEX | Jalen Richard RB | 8.40 |
| FLEX | Demaryius Thomas WR | 0.00 |
| DST | Seattle Seahawks DST | -6.00 |
| Total | 72.4 | |
| Bench | ||
| Pos | Player | Points |
| BN | Denver Broncos DST | 0.00 |
| BN | A.J. Green WR | 0.00 |
| BN | Russell Wilson QB | 18.10 |
| BN | Doug Baldwin WR | 14.70 |
| BN | DeSean Jackson WR | 9.20 |
| BN | Javorius Allen RB | 0.00 |
| BN | Charles Clay TE | 0.00 |
| BN | Alex Collins RB | 0.00 |
| BN | Mike Davis RB | 0.00 |
| BN | Jordan Wilkins RB | 5.65 |
| Bench | ||
| Pos | Player | Points |
| BN | Quincy Enunwa WR | 3.80 |
| BN | Andy Dalton QB | 6.90 |
| BN | Carson Wentz QB | 21.10 |
| BN | Mohamed Sanu WR | 5.70 |
| BN | Jesse James TE | 7.30 |
| BN | Dalvin Cook RB | 0.00 |
| BN | John Ross WR | 10.90 |
| BN | Las Vegas Raiders DST | 3.00 |
| BN | Keelan Cole WR | 0.00 |
| BN | Royce Freeman RB | 0.00 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Jared Goff QB | 21.00 | 100% |
| RB | Alvin Kamara RB | 24.30 | 75.5% |
| RB | Kerryon Johnson RB | 21.90 | |
| WR | JuJu Smith-Schuster WR | 17.80 | 69.2% |
| WR | Doug Baldwin WR | 14.70 | |
| TE | Devin Funchess TE | 4.70 | 38.3% |
| FLEX | Kareem Hunt RB | 10.60 | 151% |
| FLEX | DeSean Jackson WR | 9.20 | |
| DST | Philadelphia Eagles DST | 1.00 | 100% |
| Total | 125.2 | 88.7% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Carson Wentz QB | 21.10 | 64.9% |
| RB | Frank Gore RB | 11.20 | 97.4% |
| RB | Jalen Richard RB | 8.40 | |
| WR | Allen Robinson WR | 28.30 | 89% |
| WR | John Ross WR | 10.90 | |
| TE | Jesse James TE | 7.30 | 31.5% |
| FLEX | Adrian Peterson RB | 7.90 | 57.9% |
| FLEX | Mike Evans WR | 6.60 | |
| DST | Las Vegas Raiders DST | 3.00 | -200% |
| Total | 104.7 | 69.1% | |