| Starters | ||
| Pos | Player | Points |
| QB | Ben Roethlisberger QB | 20.30 |
| RB | Mark Ingram RB | 7.60 |
| RB | Tevin Coleman RB | 9.80 |
| WR | Amari Cooper WR | 34.00 |
| WR | Julian Edelman WR | 16.40 |
| TE | Eric Ebron TE | 19.00 |
| FLEX | Joe Mixon RB | 19.00 |
| FLEX | D.J. Moore WR | 17.55 |
| DST | Los Angeles Chargers DST | 10.00 |
| Total | 153.65 | |
| Starters | ||
| Pos | Player | Points |
| QB | Kirk Cousins QB | 27.40 |
| RB | Saquon Barkley RB | 29.70 |
| RB | Nick Chubb RB | 26.30 |
| WR | Jarvis Landry WR | 4.50 |
| WR | Courtland Sutton WR | 1.90 |
| TE | George Kittle TE | 8.80 |
| FLEX | Christian Kirk WR | 7.40 |
| FLEX | Gus Edwards RB | 11.80 |
| DST | San Francisco 49ers DST | -2.00 |
| Total | 115.8 | |
| Bench | ||
| Pos | Player | Points |
| BN | Giovani Bernard RB | 2.70 |
| BN | Kyle Rudolph TE | 9.80 |
| BN | LeSean McCoy RB | 5.80 |
| BN | Dallas Cowboys DST | 9.00 |
| BN | Kansas City Chiefs DST | 0.00 |
| BN | Deshaun Watson QB | 29.40 |
| BN | Corey Clement RB | 13.15 |
| BN | Chris Godwin WR | 6.20 |
| BN | Chris Carson RB | 13.30 |
| BN | Calvin Ridley WR | 17.30 |
| Bench | ||
| Pos | Player | Points |
| BN | Carlos Hyde RB | 3.30 |
| BN | Trey Burton TE | 2.80 |
| BN | Los Angeles Rams DST | 0.00 |
| BN | Ty Montgomery RB | 7.90 |
| BN | Larry Fitzgerald WR | 10.00 |
| BN | Golden Tate WR | 5.20 |
| BN | Jakeem Grant WR | 0.00 |
| BN | Rashaad Penny RB | 0.40 |
| BN | Nyheim Hines RB | 6.00 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Deshaun Watson QB | 29.40 | 69% |
| RB | Joe Mixon RB | 19.00 | 53.9% |
| RB | Chris Carson RB | 13.30 | |
| WR | Amari Cooper WR | 34.00 | 96.4% |
| WR | David Moore WR | 18.30 | |
| TE | Eric Ebron TE | 19.00 | 100% |
| FLEX | D.J. Moore WR | 17.55 | 104.9% |
| FLEX | Calvin Ridley WR | 17.30 | |
| DST | Los Angeles Chargers DST | 10.00 | 100% |
| Total | 177.85 | 86.4% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Kirk Cousins QB | 27.40 | 100% |
| RB | Saquon Barkley RB | 29.70 | 100% |
| RB | Nick Chubb RB | 26.30 | |
| WR | Larry Fitzgerald WR | 10.00 | 36.8% |
| WR | Christian Kirk WR | 7.40 | |
| TE | George Kittle TE | 8.80 | 100% |
| FLEX | Gus Edwards RB | 11.80 | 97.5% |
| FLEX | Ty Montgomery RB | 7.90 | |
| DST | Los Angeles Rams DST | 0.00 | -- |
| Total | 129.3 | 89.6% | |