| Starters | ||
| Pos | Player | Points |
| QB | Cam Newton QB | 22.50 |
| RB | James White RB | 8.30 |
| RB | David Johnson RB | 8.90 |
| WR | Odell Beckham WR | 11.80 |
| WR | Tyler Lockett WR | 19.00 |
| TE | Rob Gronkowski TE | 13.10 |
| FLEX | Theo Riddick RB | 9.50 |
| FLEX | Anthony Miller WR | 5.90 |
| DST | Carolina Panthers DST | 0.00 |
| Total | 99 | |
| Starters | ||
| Pos | Player | Points |
| QB | Baker Mayfield QB | 25.90 |
| RB | Alfred Morris RB | 0.00 |
| RB | Latavius Murray RB | 3.30 |
| WR | Kelvin Benjamin WR | 3.70 |
| WR | Tyrell Williams WR | 0.00 |
| TE | Greg Olsen TE | 2.10 |
| FLEX | Randall Cobb WR | 0.00 |
| FLEX | Antonio Callaway WR | 14.90 |
| DST | Pittsburgh Steelers DST | 2.00 |
| Total | 51.9 | |
| Bench | ||
| Pos | Player | Points |
| BN | Spencer Ware RB | 0.00 |
| BN | Philip Rivers QB | 20.70 |
| BN | Donte Moncrief WR | 3.40 |
| BN | Willie Snead WR | 0.00 |
| BN | Cameron Brate TE | 10.10 |
| BN | Travis Kelce TE | 0.00 |
| BN | Taylor Gabriel WR | 8.40 |
| BN | Green Bay Packers DST | -1.00 |
| BN | Austin Ekeler RB | 21.30 |
| BN | Dallas Goedert TE | 4.80 |
| Bench | ||
| Pos | Player | Points |
| BN | Jordy Nelson WR | -0.20 |
| BN | Arizona Cardinals DST | 0.00 |
| BN | Nelson Agholor WR | 1.70 |
| BN | Blake Bortles QB | 9.00 |
| BN | Matthew Stafford QB | 5.40 |
| BN | Chris Hogan WR | 5.70 |
| BN | O.J. Howard TE | 0.00 |
| BN | Paul Richardson WR | 0.00 |
| BN | Ian Thomas TE | 0.00 |
| BN | TreQuan Smith WR | 0.00 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Cam Newton QB | 22.50 | 100% |
| RB | Austin Ekeler RB | 21.30 | 55.8% |
| RB | Theo Riddick RB | 9.50 | |
| WR | Tyler Lockett WR | 19.00 | 91.4% |
| WR | Adam Humphries WR | 14.70 | |
| TE | Rob Gronkowski TE | 13.10 | 100% |
| FLEX | Odell Beckham WR | 11.80 | 70.3% |
| FLEX | Cameron Brate TE | 10.10 | |
| DST | Carolina Panthers DST | 0.00 | -- |
| Total | 122 | 81.1% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Baker Mayfield QB | 25.90 | 100% |
| RB | Latavius Murray RB | 3.30 | 100% |
| RB | Jerick McKinnon RB | 0.00 | |
| WR | Antonio Callaway WR | 14.90 | 18% |
| WR | Chris Hogan WR | 5.70 | |
| TE | Greg Olsen TE | 2.10 | 100% |
| FLEX | Kelvin Benjamin WR | 3.70 | 275.9% |
| FLEX | Nelson Agholor WR | 1.70 | |
| DST | Pittsburgh Steelers DST | 2.00 | 100% |
| Total | 59.3 | 87.5% | |