| Starters | ||
| Pos | Player | Points |
| QB | Aaron Rodgers QB | 12.90 |
| RB | Mark Ingram RB | 22.70 |
| RB | Leonard Fournette RB | 9.40 |
| WR | DeAndre Hopkins WR | 27.10 |
| WR | Kenny Golladay WR | 12.20 |
| TE | Evan Engram TE | 23.10 |
| FLEX | Sony Michel RB | 1.40 |
| FLEX | Phillip Lindsay RB | 8.60 |
| DST | Chicago Bears DST | 10.00 |
| Total | 127.4 | |
| Starters | ||
| Pos | Player | Points |
| QB | Jameis Winston QB | 7.10 |
| RB | David Johnson RB | 22.70 |
| RB | Christian McCaffrey RB | 37.90 |
| WR | Davante Adams WR | 5.60 |
| WR | Brandin Cooks WR | 4.90 |
| TE | Zach Ertz TE | 7.90 |
| FLEX | James Conner RB | 8.50 |
| FLEX | Aaron Jones RB | 4.40 |
| DST | Seattle Seahawks DST | 8.00 |
| Total | 107 | |
| Bench | ||
| Pos | Player | Points |
| BN | Marcus Mariota QB | 24.30 |
| BN | Sterling Shepard WR | 7.20 |
| BN | Tyrell Williams WR | 19.50 |
| BN | Latavius Murray RB | 11.70 |
| BN | Jaylen Samuels RB | 1.10 |
| BN | Parris Campbell WR | 1.30 |
| BN | Darwin Thompson RB | 0.80 |
| BN | Diontae Johnson WR | 4.00 |
| BN | Terry McLaurin WR | 21.00 |
| BN | D.K. Metcalf WR | 10.90 |
| BN | Hakeem Butler TE | |
| BN | T.J. Hockenson TE | 22.10 |
| Bench | ||
| Pos | Player | Points |
| BN | Alfred Morris RB | |
| BN | Pittsburgh Steelers DST | -5.00 |
| BN | T.Y. Hilton WR | 24.70 |
| BN | Jack Doyle TE | 2.50 |
| BN | Marvin Jones WR | 8.00 |
| BN | Miami Dolphins DST | -11.00 |
| BN | Robby Anderson WR | 3.80 |
| BN | T.J. Jones WR | |
| BN | Josh Allen QB | 16.00 |
| BN | Equanimeous St. Brown WR | |
| BN | Mike Weber RB | |
| BN | Benny Snell Jr. RB | |
| BN | Jordan Scarlett RB | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Marcus Mariota QB | 24.30 | 53.1% |
| RB | Mark Ingram RB | 22.70 | 93.3% |
| RB | Latavius Murray RB | 11.70 | |
| WR | DeAndre Hopkins WR | 27.10 | 81.7% |
| WR | Terry McLaurin WR | 21.00 | |
| TE | Evan Engram TE | 23.10 | 100% |
| FLEX | T.J. Hockenson TE | 22.10 | 24% |
| FLEX | Tyrell Williams WR | 19.50 | |
| DST | Chicago Bears DST | 10.00 | 100% |
| Total | 181.5 | 70.2% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Josh Allen QB | 16.00 | 44.4% |
| RB | Christian McCaffrey RB | 37.90 | 100% |
| RB | David Johnson RB | 22.70 | |
| WR | T.Y. Hilton WR | 24.70 | 32.1% |
| WR | Marvin Jones WR | 8.00 | |
| TE | Zach Ertz TE | 7.90 | 100% |
| FLEX | James Conner RB | 8.50 | 91.5% |
| FLEX | Davante Adams WR | 5.60 | |
| DST | Seattle Seahawks DST | 8.00 | 100% |
| Total | 139.3 | 76.8% | |