| Starters | ||
| Pos | Player | Points |
| QB | Josh Allen QB | 18.30 |
| RB | David Johnson RB | 15.50 |
| RB | Christian McCaffrey RB | 26.30 |
| WR | T.Y. Hilton WR | 16.50 |
| WR | Davante Adams WR | 7.60 |
| TE | Zach Ertz TE | 8.40 |
| FLEX | Brandin Cooks WR | 16.00 |
| FLEX | Aaron Jones RB | 14.80 |
| DST | Seattle Seahawks DST | 4.00 |
| Total | 127.4 | |
| Starters | ||
| Pos | Player | Points |
| QB | Derek Carr QB | 15.70 |
| RB | Derrick Henry RB | 11.10 |
| RB | Austin Ekeler RB | 11.60 |
| WR | Julio Jones WR | 22.80 |
| WR | Mecole Hardman WR | 17.40 |
| TE | Travis Kelce TE | 12.40 |
| FLEX | Jamaal Williams RB | 9.60 |
| FLEX | James Washington WR | 2.40 |
| DST | Green Bay Packers DST | 13.00 |
| Total | 116 | |
| Bench | ||
| Pos | Player | Points |
| BN | Pittsburgh Steelers DST | 8.00 |
| BN | Jack Doyle TE | 6.60 |
| BN | Jameis Winston QB | 25.50 |
| BN | Jamison Crowder WR | 3.50 |
| BN | Marvin Jones WR | 19.10 |
| BN | Miami Dolphins DST | -3.00 |
| BN | Robby Anderson WR | 2.60 |
| BN | James Conner RB | 5.70 |
| Bench | ||
| Pos | Player | Points |
| BN | James White RB | |
| BN | Cam Newton QB | |
| BN | Taylor Gabriel WR | 29.20 |
| BN | Rashard Higgins WR | |
| BN | Carolina Panthers DST | 14.00 |
| BN | Chase Edmonds RB | 3.00 |
| BN | Dallas Goedert TE | |
| BN | Anthony Miller WR | 2.00 |
| BN | Darrell Henderson RB | |
| BN | Dare Ogunbowale RB | 3.80 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Jameis Winston QB | 25.50 | 71.8% |
| RB | Christian McCaffrey RB | 26.30 | 100% |
| RB | David Johnson RB | 15.50 | |
| WR | Marvin Jones WR | 19.10 | 67.7% |
| WR | T.Y. Hilton WR | 16.50 | |
| TE | Zach Ertz TE | 8.40 | 100% |
| FLEX | Brandin Cooks WR | 16.00 | 100% |
| FLEX | Aaron Jones RB | 14.80 | |
| DST | Pittsburgh Steelers DST | 8.00 | 50% |
| Total | 150.1 | 84.9% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Derek Carr QB | 15.70 | 100% |
| RB | Austin Ekeler RB | 11.60 | 100% |
| RB | Derrick Henry RB | 11.10 | |
| WR | Taylor Gabriel WR | 29.20 | 77.3% |
| WR | Julio Jones WR | 22.80 | |
| TE | Travis Kelce TE | 12.40 | 100% |
| FLEX | Mecole Hardman WR | 17.40 | 40.4% |
| FLEX | Adam Humphries WR | 12.30 | |
| DST | Carolina Panthers DST | 14.00 | 92.9% |
| Total | 146.5 | 79.2% | |