| Starters | ||
| Pos | Player | Points |
| QB | Jacoby Brissett QB | 22.50 |
| RB | Jordan Howard RB | 31.00 |
| RB | Marlon Mack RB | 3.90 |
| WR | Tyler Lockett WR | 7.10 |
| WR | Michael Thomas WR | 14.00 |
| TE | Darren Waller TE | 8.80 |
| FLEX | Sammy Watkins WR | 4.90 |
| FLEX | Preston Williams WR | 6.60 |
| DST | Indianapolis Colts DST | 2.00 |
| Total | 100.8 | |
| Starters | ||
| Pos | Player | Points |
| QB | Aaron Rodgers QB | 25.50 |
| RB | Mark Ingram RB | 7.60 |
| RB | Leonard Fournette RB | 25.50 |
| WR | DeAndre Hopkins WR | 4.60 |
| WR | Kenny Golladay WR | 21.20 |
| TE | Evan Engram TE | 7.40 |
| FLEX | Sterling Shepard WR | 13.40 |
| FLEX | Phillip Lindsay RB | 6.50 |
| DST | Chicago Bears DST | 16.00 |
| Total | 127.7 | |
| Bench | ||
| Pos | Player | Points |
| BN | Jimmy Garoppolo QB | |
| BN | Greg Olsen TE | 1.50 |
| BN | Phillip Dorsett WR | 2.90 |
| BN | Corey Davis WR | 17.60 |
| BN | Tennessee Titans DST | 7.00 |
| BN | Raheem Mostert RB | |
| BN | Kalen Ballage RB | 0.70 |
| BN | Chris Herndon IV TE | |
| BN | Ty Johnson RB | 1.90 |
| BN | Damien Harris RB | |
| Bench | ||
| Pos | Player | Points |
| BN | Andy Dalton QB | 3.60 |
| BN | Tyrell Williams WR | 11.10 |
| BN | Latavius Murray RB | 2.50 |
| BN | Sony Michel RB | 6.30 |
| BN | Jaylen Samuels RB | 19.50 |
| BN | Parris Campbell WR | 3.00 |
| BN | Darwin Thompson RB | |
| BN | Terry McLaurin WR | |
| BN | D.K. Metcalf WR | 1.10 |
| BN | T.J. Hockenson TE | 10.20 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Jacoby Brissett QB | 22.50 | 100% |
| RB | Jordan Howard RB | 31.00 | 100% |
| RB | Marlon Mack RB | 3.90 | |
| WR | Corey Davis WR | 17.60 | 66.8% |
| WR | Michael Thomas WR | 14.00 | |
| TE | Noah Fant TE | 10.10 | 87.1% |
| FLEX | Miles Boykin WR | 10.70 | 59% |
| FLEX | Darren Waller TE | 8.80 | |
| DST | Tennessee Titans DST | 7.00 | 28.6% |
| Total | 125.6 | 80.3% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Aaron Rodgers QB | 25.50 | 100% |
| RB | Leonard Fournette RB | 25.50 | 73.6% |
| RB | Jaylen Samuels RB | 19.50 | |
| WR | Kenny Golladay WR | 21.20 | 71.9% |
| WR | Diontae Johnson WR | 14.70 | |
| TE | T.J. Hockenson TE | 10.20 | 72.5% |
| FLEX | Sterling Shepard WR | 13.40 | 81.2% |
| FLEX | Tyrell Williams WR | 11.10 | |
| DST | Chicago Bears DST | 16.00 | 100% |
| Total | 157.1 | 81.3% | |