| Starters | ||
| Pos | Player | Points |
| QB | Deshaun Watson QB | 11.60 |
| RB | Joe Mixon RB | 8.30 |
| RB | Chris Carson RB | 16.50 |
| WR | Amari Cooper WR | 7.30 |
| WR | Keenan Allen WR | 7.30 |
| TE | Mark Andrews TE | 11.10 |
| FLEX | Chris Godwin WR | 35.20 |
| FLEX | Hollywood Brown WR | 4.20 |
| DST | Atlanta Falcons DST | -1.00 |
| Total | 100.5 | |
| Starters | ||
| Pos | Player | Points |
| QB | Dak Prescott QB | 7.60 |
| RB | Ezekiel Elliott RB | 13.50 |
| RB | Rex Burkhead RB | 1.20 |
| WR | Josh Gordon WR | 6.10 |
| WR | Demarcus Robinson WR | 5.50 |
| TE | Jason Witten TE | 5.00 |
| FLEX | John Ross WR | 5.10 |
| FLEX | Curtis Samuel WR | 4.80 |
| DST | Minnesota Vikings DST | 4.00 |
| Total | 52.8 | |
| Bench | ||
| Pos | Player | Points |
| BN | Will Fuller WR | 3.80 |
| BN | Delanie Walker TE | 0.90 |
| BN | Tevin Coleman RB | |
| BN | Dallas Cowboys DST | 12.00 |
| BN | Julian Edelman WR | 5.00 |
| BN | Emmanuel Sanders WR | 12.90 |
| BN | Matthew Stafford QB | 23.40 |
| BN | Tony Pollard RB | |
| BN | Deebo Samuel WR | |
| BN | Darrel Williams RB | 17.10 |
| Bench | ||
| Pos | Player | Points |
| BN | Antonio Brown WR | |
| BN | Giovani Bernard RB | 3.90 |
| BN | Melvin Gordon RB | |
| BN | Nelson Agholor WR | |
| BN | Mohamed Sanu WR | 13.60 |
| BN | Buffalo Bills DST | 5.00 |
| BN | Danny Amendola WR | |
| BN | Matt Breida RB | |
| BN | Vance McDonald TE | |
| BN | Justin Jackson RB | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Matthew Stafford QB | 23.40 | 49.6% |
| RB | Darrel Williams RB | 17.10 | 73.8% |
| RB | Chris Carson RB | 16.50 | |
| WR | Chris Godwin WR | 35.20 | 30.4% |
| WR | Emmanuel Sanders WR | 12.90 | |
| TE | Mark Andrews TE | 11.10 | 100% |
| FLEX | Ito Smith RB | 10.10 | 214.1% |
| FLEX | Joe Mixon RB | 8.30 | |
| DST | Dallas Cowboys DST | 12.00 | -8.3% |
| Total | 146.6 | 68.6% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Philip Rivers QB | 20.40 | 37.3% |
| RB | Ezekiel Elliott RB | 13.50 | 84.5% |
| RB | Giovani Bernard RB | 3.90 | |
| WR | Mohamed Sanu WR | 13.60 | 58.9% |
| WR | Josh Gordon WR | 6.10 | |
| TE | Jason Witten TE | 5.00 | 100% |
| FLEX | Demarcus Robinson WR | 5.50 | 93.4% |
| FLEX | John Ross WR | 5.10 | |
| DST | Buffalo Bills DST | 5.00 | 80% |
| Total | 78.1 | 67.6% | |