| Starters | ||
| Pos | Player | Points |
| QB | Tom Brady QB | 23.90 |
| RB | Frank Gore RB | 7.90 |
| RB | Dalvin Cook RB | 22.80 |
| WR | Allen Robinson WR | 25.20 |
| WR | Mike Evans WR | |
| TE | Eric Ebron TE | 1.30 |
| FLEX | Wayne Gallman RB | 1.40 |
| FLEX | Marquez Valdes-Scantling WR | 2.30 |
| DST | New England Patriots DST | 15.00 |
| Total | 99.8 | |
| Starters | ||
| Pos | Player | Points |
| QB | Deshaun Watson QB | 41.70 |
| RB | Joe Mixon RB | 11.40 |
| RB | Chris Carson RB | 18.80 |
| WR | Amari Cooper WR | 34.10 |
| WR | Keenan Allen WR | 3.80 |
| TE | Mark Andrews TE | 7.00 |
| FLEX | Julian Edelman WR | 21.00 |
| FLEX | Chris Godwin WR | 28.00 |
| DST | Dallas Cowboys DST | 1.00 |
| Total | 166.8 | |
| Bench | ||
| Pos | Player | Points |
| BN | Peyton Barber RB | 9.60 |
| BN | Randall Cobb WR | 6.80 |
| BN | Kenyan Drake RB | |
| BN | Hunter Henry TE | |
| BN | Dion Lewis RB | 4.00 |
| BN | Adrian Peterson RB | 1.80 |
| BN | David Njoku TE | |
| BN | Royce Freeman RB | 7.70 |
| BN | Kyler Murray QB | 25.40 |
| BN | NKeal Harry TE | |
| Bench | ||
| Pos | Player | Points |
| BN | Will Fuller WR | 46.70 |
| BN | Delanie Walker TE | 1.50 |
| BN | Tevin Coleman RB | 15.70 |
| BN | Atlanta Falcons DST | -10.00 |
| BN | Emmanuel Sanders WR | 1.40 |
| BN | Matthew Stafford QB | |
| BN | Tony Pollard RB | 1.90 |
| BN | Deebo Samuel WR | 0.80 |
| BN | Hollywood Brown WR | 9.70 |
| BN | Darrel Williams RB | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Kyler Murray QB | 25.40 | 94.1% |
| RB | Dalvin Cook RB | 22.80 | 94.8% |
| RB | Peyton Barber RB | 9.60 | |
| WR | Allen Robinson WR | 25.20 | 78.8% |
| WR | Randall Cobb WR | 6.80 | |
| TE | Hayden Hurst TE | 5.20 | 25% |
| FLEX | Frank Gore RB | 7.90 | 23.7% |
| FLEX | Royce Freeman RB | 7.70 | |
| DST | New England Patriots DST | 15.00 | 100% |
| Total | 125.6 | 79.5% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Deshaun Watson QB | 41.70 | 100% |
| RB | Chris Carson RB | 18.80 | 87.5% |
| RB | Tevin Coleman RB | 15.70 | |
| WR | Will Fuller WR | 46.70 | 46.9% |
| WR | Amari Cooper WR | 34.10 | |
| TE | Mark Andrews TE | 7.00 | 100% |
| FLEX | Chris Godwin WR | 28.00 | 100% |
| FLEX | Julian Edelman WR | 21.00 | |
| DST | Dallas Cowboys DST | 1.00 | 100% |
| Total | 214 | 77.9% | |