| Starters | ||
| Pos | Player | Points |
| QB | Carson Wentz QB | 12.10 |
| RB | Todd Gurley RB | 17.20 |
| RB | Miles Sanders RB | 8.40 |
| WR | Cooper Kupp WR | 22.20 |
| WR | D.J. Moore WR | 12.10 |
| TE | Will Dissly TE | 10.80 |
| FLEX | Stefon Diggs WR | 5.90 |
| FLEX | Devonta Freeman RB | 15.50 |
| DST | Cleveland Browns DST | 0.00 |
| Total | 104.2 | |
| Starters | ||
| Pos | Player | Points |
| QB | Jameis Winston QB | 17.50 |
| RB | David Johnson RB | 17.10 |
| RB | Christian McCaffrey RB | 44.70 |
| WR | T.Y. Hilton WR | 5.70 |
| WR | Brandin Cooks WR | 6.10 |
| TE | Zach Ertz TE | 14.20 |
| FLEX | James Conner RB | 11.50 |
| FLEX | Aaron Jones RB | 45.70 |
| DST | Pittsburgh Steelers DST | 13.00 |
| Total | 175.5 | |
| Bench | ||
| Pos | Player | Points |
| BN | John Brown WR | 10.00 |
| BN | Malcolm Brown RB | 0.30 |
| BN | Gerald Everett TE | 17.10 |
| BN | New Orleans Saints DST | 8.00 |
| BN | Sam Darnold QB | |
| BN | Ronald Jones II RB | 6.60 |
| BN | Calvin Ridley WR | 17.30 |
| BN | Dante Pettis WR | 1.60 |
| BN | Keesean Johnson WR | 4.00 |
| BN | Andy Isabella WR | 1.10 |
| Bench | ||
| Pos | Player | Points |
| BN | Jack Doyle TE | 3.40 |
| BN | Davante Adams WR | |
| BN | Jamison Crowder WR | 2.00 |
| BN | Seattle Seahawks DST | -2.00 |
| BN | Marvin Jones WR | |
| BN | Miami Dolphins DST | 0.00 |
| BN | Robby Anderson WR | 2.10 |
| BN | Josh Allen QB | 17.50 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Carson Wentz QB | 12.10 | 100% |
| RB | Todd Gurley RB | 17.20 | 78.3% |
| RB | Devonta Freeman RB | 15.50 | |
| WR | Cooper Kupp WR | 22.20 | 86.8% |
| WR | Calvin Ridley WR | 17.30 | |
| TE | Gerald Everett TE | 17.10 | 63.2% |
| FLEX | D.J. Moore WR | 12.10 | 93.4% |
| FLEX | Will Dissly TE | 10.80 | |
| DST | New Orleans Saints DST | 8.00 | 0% |
| Total | 132.3 | 78.8% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Josh Allen QB | 17.50 | 100% |
| RB | Aaron Jones RB | 45.70 | 68.4% |
| RB | Christian McCaffrey RB | 44.70 | |
| WR | Brandin Cooks WR | 6.10 | 100% |
| WR | T.Y. Hilton WR | 5.70 | |
| TE | Zach Ertz TE | 14.20 | 100% |
| FLEX | David Johnson RB | 17.10 | 200% |
| FLEX | James Conner RB | 11.50 | |
| DST | Pittsburgh Steelers DST | 13.00 | 100% |
| Total | 175.5 | 100% | |