| Starters | ||
| Pos | Player | Points |
| QB | Kyler Murray QB | 10.10 |
| RB | Dalvin Cook RB | 25.60 |
| RB | Royce Freeman RB | 11.00 |
| WR | Allen Robinson WR | 8.70 |
| WR | Mike Evans WR | 37.30 |
| TE | Hunter Henry TE | 6.70 |
| FLEX | Frank Gore RB | 3.40 |
| FLEX | Marquez Valdes-Scantling WR | 0.90 |
| DST | New England Patriots DST | 20.00 |
| Total | 123.7 | |
| Starters | ||
| Pos | Player | Points |
| QB | Patrick Mahomes QB | |
| RB | LeVeon Bell RB | 5.00 |
| RB | Devin Singletary RB | 12.90 |
| WR | Odell Beckham WR | 7.70 |
| WR | Tyreek Hill WR | 11.10 |
| TE | Kyle Rudolph TE | 3.20 |
| FLEX | LeSean McCoy RB | 6.30 |
| FLEX | Tarik Cohen RB | 6.10 |
| DST | Houston Texans DST | -1.00 |
| Total | 51.3 | |
| Bench | ||
| Pos | Player | Points |
| BN | Peyton Barber RB | 3.30 |
| BN | Tom Brady QB | 18.40 |
| BN | Randall Cobb WR | |
| BN | Kenyan Drake RB | |
| BN | Dion Lewis RB | 0.70 |
| BN | Adrian Peterson RB | 11.30 |
| BN | David Njoku TE | |
| BN | Hayden Hurst TE | |
| BN | Auden Tate WR | 9.00 |
| BN | NKeal Harry TE | |
| Bench | ||
| Pos | Player | Points |
| BN | Jared Cook TE | |
| BN | Chris Thompson RB | |
| BN | Joe Flacco QB | 7.90 |
| BN | Baltimore Ravens DST | 0.00 |
| BN | Geronimo Allison WR | 1.20 |
| BN | DOnta Foreman RB | |
| BN | Adam Thielen WR | |
| BN | Kenny Stills WR | 3.70 |
| BN | Lamar Jackson QB | |
| BN | Justice Hill RB | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Tom Brady QB | 18.40 | 54.9% |
| RB | Dalvin Cook RB | 25.60 | 99.2% |
| RB | Adrian Peterson RB | 11.30 | |
| WR | Mike Evans WR | 37.30 | 92% |
| WR | Alex Erickson WR | 12.70 | |
| TE | Hunter Henry TE | 6.70 | 100% |
| FLEX | Royce Freeman RB | 11.00 | 21.5% |
| FLEX | Auden Tate WR | 9.00 | |
| DST | New England Patriots DST | 20.00 | 100% |
| Total | 152 | 81.4% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Joe Flacco QB | 7.90 | 0% |
| RB | Devin Singletary RB | 12.90 | 93.2% |
| RB | LeSean McCoy RB | 6.30 | |
| WR | Tyreek Hill WR | 11.10 | 100% |
| WR | Odell Beckham WR | 7.70 | |
| TE | Kyle Rudolph TE | 3.20 | 100% |
| FLEX | Tarik Cohen RB | 6.10 | 111.7% |
| FLEX | LeVeon Bell RB | 5.00 | |
| DST | Baltimore Ravens DST | 0.00 | -- |
| Total | 60.2 | 85.2% | |