| Starters | ||
| Pos | Player | Points |
| QB | Derek Carr QB | 13.10 |
| RB | Derrick Henry RB | 32.10 |
| RB | Austin Ekeler RB | 11.80 |
| WR | Julio Jones WR | 9.40 |
| WR | Cole Beasley WR | 9.40 |
| TE | Travis Kelce TE | 17.00 |
| FLEX | Adam Humphries WR | 8.80 |
| FLEX | Jamaal Williams RB | 6.30 |
| DST | Green Bay Packers DST | 5.00 |
| Total | 112.9 | |
| Starters | ||
| Pos | Player | Points |
| QB | Aaron Rodgers QB | 10.00 |
| RB | Aaron Jones RB | 27.30 |
| RB | Christian McCaffrey RB | 23.10 |
| WR | Davante Adams WR | 15.30 |
| WR | Jamison Crowder WR | 16.60 |
| TE | Jack Doyle TE | 11.90 |
| FLEX | David Johnson RB | -0.50 |
| FLEX | Marvin Jones WR | 10.20 |
| DST | Pittsburgh Steelers DST | 22.00 |
| Total | 135.9 | |
| Bench | ||
| Pos | Player | Points |
| BN | James White RB | |
| BN | Taylor Gabriel WR | 11.80 |
| BN | Carolina Panthers DST | 1.00 |
| BN | Chase Edmonds RB | |
| BN | Dallas Goedert TE | |
| BN | Anthony Miller WR | 1.20 |
| BN | James Washington WR | 16.00 |
| BN | Mecole Hardman WR | 12.80 |
| BN | Darrell Henderson RB | 0.40 |
| BN | Gardner Minshew QB | |
| Bench | ||
| Pos | Player | Points |
| BN | T.Y. Hilton WR | |
| BN | Jameis Winston QB | 18.30 |
| BN | Seattle Seahawks DST | 17.00 |
| BN | Brandin Cooks WR | |
| BN | Zach Ertz TE | |
| BN | Robby Anderson WR | 1.60 |
| BN | James Conner RB | |
| BN | Josh Allen QB | 25.40 |
| BN | Phillip Lindsay RB | |
| BN | Benny Snell Jr. RB | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Derek Carr QB | 13.10 | 100% |
| RB | Derrick Henry RB | 32.10 | 100% |
| RB | Austin Ekeler RB | 11.80 | |
| WR | James Washington WR | 16.00 | 65.3% |
| WR | Mecole Hardman WR | 12.80 | |
| TE | Travis Kelce TE | 17.00 | 100% |
| FLEX | Taylor Gabriel WR | 11.80 | 71.2% |
| FLEX | Julio Jones WR | 9.40 | |
| DST | Green Bay Packers DST | 5.00 | 100% |
| Total | 129 | 87.5% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Josh Allen QB | 25.40 | 39.4% |
| RB | Aaron Jones RB | 27.30 | 100% |
| RB | Christian McCaffrey RB | 23.10 | |
| WR | Jamison Crowder WR | 16.60 | 100% |
| WR | Davante Adams WR | 15.30 | |
| TE | Jack Doyle TE | 11.90 | 100% |
| FLEX | Marvin Jones WR | 10.20 | 82.2% |
| FLEX | Robby Anderson WR | 1.60 | |
| DST | Pittsburgh Steelers DST | 22.00 | 100% |
| Total | 153.4 | 88.6% | |