| Starters | ||
| Pos | Player | Points |
| QB | Derek Carr QB | 19.80 |
| RB | James White RB | 7.60 |
| RB | Austin Ekeler RB | 17.20 |
| WR | Julio Jones WR | 11.70 |
| WR | Cole Beasley WR | 5.80 |
| TE | Travis Kelce TE | 18.70 |
| FLEX | Taylor Gabriel WR | 9.20 |
| FLEX | James Washington WR | 6.40 |
| DST | Carolina Panthers DST | 2.00 |
| Total | 98.4 | |
| Starters | ||
| Pos | Player | Points |
| QB | Kirk Cousins QB | 22.90 |
| RB | Nick Chubb RB | 9.20 |
| RB | David Montgomery RB | 5.50 |
| WR | Mike Williams WR | 8.60 |
| WR | Christian Kirk WR | 7.20 |
| TE | George Kittle TE | |
| FLEX | Jarvis Landry WR | 12.30 |
| FLEX | Courtland Sutton WR | 16.30 |
| DST | San Francisco 49ers DST | 16.00 |
| Total | 98 | |
| Bench | ||
| Pos | Player | Points |
| BN | Derrick Henry RB | |
| BN | Green Bay Packers DST | 0.00 |
| BN | Adam Humphries WR | |
| BN | Jamaal Williams RB | |
| BN | Chase Edmonds RB | |
| BN | Dallas Goedert TE | 11.10 |
| BN | Anthony Miller WR | 8.40 |
| BN | Mecole Hardman WR | 2.30 |
| BN | Darrell Henderson RB | |
| BN | Gardner Minshew QB | |
| Bench | ||
| Pos | Player | Points |
| BN | Trey Burton TE | |
| BN | Los Angeles Rams DST | 10.00 |
| BN | Larry Fitzgerald WR | 10.20 |
| BN | Golden Tate WR | |
| BN | Saquon Barkley RB | |
| BN | Rashaad Penny RB | |
| BN | Gus Edwards RB | 17.20 |
| BN | Daniel Jones QB | |
| BN | A.J. Brown WR | |
| BN | Alexander Mattison RB | 0.50 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Derek Carr QB | 19.80 | 100% |
| RB | Austin Ekeler RB | 17.20 | 100% |
| RB | James White RB | 7.60 | |
| WR | Julio Jones WR | 11.70 | 83.7% |
| WR | Taylor Gabriel WR | 9.20 | |
| TE | Travis Kelce TE | 18.70 | 100% |
| FLEX | Dallas Goedert TE | 11.10 | 80% |
| FLEX | Anthony Miller WR | 8.40 | |
| DST | Carolina Panthers DST | 2.00 | 100% |
| Total | 105.7 | 93.1% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Kirk Cousins QB | 22.90 | 100% |
| RB | Gus Edwards RB | 17.20 | 55.7% |
| RB | Nick Chubb RB | 9.20 | |
| WR | DeVante Parker WR | 17.00 | 47.4% |
| WR | Courtland Sutton WR | 16.30 | |
| TE | Jacob Hollister TE | -- | |
| FLEX | Jarvis Landry WR | 12.30 | 127.1% |
| FLEX | Larry Fitzgerald WR | 10.20 | |
| DST | San Francisco 49ers DST | 16.00 | 100% |
| Total | 121.1 | 80.9% | |