| Starters | ||
| Pos | Player | Points |
| QB | Mitch Trubisky QB | 18.90 |
| RB | Jaylen Samuels RB | 4.70 |
| RB | Josh Jacobs RB | 4.10 |
| WR | DeAndre Hopkins WR | 24.40 |
| WR | Kenny Golladay WR | 8.10 |
| TE | T.J. Hockenson TE | |
| FLEX | Terry McLaurin WR | 9.70 |
| FLEX | D.K. Metcalf WR | 5.00 |
| DST | Chicago Bears DST | 6.00 |
| Total | 80.9 | |
| Starters | ||
| Pos | Player | Points |
| QB | Daniel Jones QB | 14.70 |
| RB | Saquon Barkley RB | 7.00 |
| RB | Nick Chubb RB | 23.90 |
| WR | Jarvis Landry WR | 31.80 |
| WR | Courtland Sutton WR | 3.20 |
| TE | George Kittle TE | 21.90 |
| FLEX | A.J. Brown WR | 21.50 |
| FLEX | David Montgomery RB | 4.10 |
| DST | Los Angeles Rams DST | -5.00 |
| Total | 123.1 | |
| Bench | ||
| Pos | Player | Points |
| BN | Ryan Fitzpatrick QB | 23.10 |
| BN | Sterling Shepard WR | 6.20 |
| BN | Brian Hill RB | 4.20 |
| BN | Evan Engram TE | |
| BN | Las Vegas Raiders DST | -1.00 |
| BN | J.D. McKissic RB | 3.00 |
| BN | Sony Michel RB | 8.50 |
| BN | Parris Campbell WR | |
| BN | Diontae Johnson WR | 4.40 |
| BN | JJ Arcega-Whiteside WR | 5.30 |
| Bench | ||
| Pos | Player | Points |
| BN | Trey Burton TE | |
| BN | Kirk Cousins QB | |
| BN | Larry Fitzgerald WR | |
| BN | Golden Tate WR | 10.80 |
| BN | San Francisco 49ers DST | 13.00 |
| BN | Mike Williams WR | |
| BN | Rashaad Penny RB | 18.90 |
| BN | Christian Kirk WR | |
| BN | Gus Edwards RB | 5.50 |
| BN | Alexander Mattison RB | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Ryan Fitzpatrick QB | 23.10 | 81.8% |
| RB | Sony Michel RB | 8.50 | 66.7% |
| RB | Jaylen Samuels RB | 4.70 | |
| WR | DeAndre Hopkins WR | 24.40 | 95.3% |
| WR | Terry McLaurin WR | 9.70 | |
| TE | Evan Engram TE | -- | |
| FLEX | Kenny Golladay WR | 8.10 | 102.8% |
| FLEX | Sterling Shepard WR | 6.20 | |
| DST | Chicago Bears DST | 6.00 | 100% |
| Total | 90.7 | 89.2% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Nick Foles QB | 14.90 | 98.7% |
| RB | Nick Chubb RB | 23.90 | 72.2% |
| RB | Rashaad Penny RB | 18.90 | |
| WR | Jarvis Landry WR | 31.80 | 65.7% |
| WR | A.J. Brown WR | 21.50 | |
| TE | George Kittle TE | 21.90 | 100% |
| FLEX | DeVante Parker WR | 12.10 | 111.8% |
| FLEX | Golden Tate WR | 10.80 | |
| DST | San Francisco 49ers DST | 13.00 | -38.5% |
| Total | 168.8 | 72.9% | |