| Starters | ||
| Pos | Player | Points |
| QB | Carson Wentz QB | 21.40 |
| RB | Isaiah Crowell RB | 8.30 |
| RB | Jonathan Stewart RB | -0.40 |
| WR | Mike Evans WR | 17.00 |
| WR | Demaryius Thomas WR | 16.30 |
| TE | David Njoku TE | 1.00 |
| FLEX | Doug Martin RB | 14.90 |
| FLEX | Eric Decker WR | 12.30 |
| DST | Las Vegas Raiders DST | 4.00 |
| Total | 94.8 | |
| Starters | ||
| Pos | Player | Points |
| QB | Drew Brees QB | 11.50 |
| RB | Mark Ingram RB | 27.50 |
| RB | Matt Breida RB | 4.60 |
| WR | Antonio Brown WR | 25.50 |
| WR | Jordy Nelson WR | 9.00 |
| TE | Delanie Walker TE | 3.40 |
| FLEX | Michael Crabtree WR | 14.20 |
| FLEX | Terrelle Pryor WR | 3.80 |
| DST | Washington Commanders DST | 5.00 |
| Total | 104.5 | |
| Bench | ||
| Pos | Player | Points |
| BN | Quincy Enunwa WR | 0.00 |
| BN | Derek Carr QB | 6.80 |
| BN | Rob Kelley RB | 0.00 |
| BN | Corey Coleman WR | 0.00 |
| BN | Allen Hurns WR | 5.20 |
| BN | Mohamed Sanu WR | 0.00 |
| BN | Seattle Seahawks DST | 0.00 |
| BN | Jesse James TE | 0.00 |
| BN | Matt Forte RB | 12.10 |
| BN | John Ross WR | 0.00 |
| Bench | ||
| Pos | Player | Points |
| BN | Wendell Smallwood RB | 0.00 |
| BN | Martavis Bryant WR | 3.70 |
| BN | New York Jets DST | 3.00 |
| BN | LeSean McCoy RB | 0.00 |
| BN | Robby Anderson WR | 9.60 |
| BN | Deshaun Watson QB | 23.30 |
| BN | Wayne Gallman RB | 4.20 |
| BN | James Conner RB | 1.40 |
| BN | Joe Mixon RB | 0.00 |
| BN | Benjamin Watson TE | 5.80 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Carson Wentz QB | 21.40 | 100% |
| RB | Doug Martin RB | 14.90 | 29.3% |
| RB | Matt Forte RB | 12.10 | |
| WR | Mike Evans WR | 17.00 | 100% |
| WR | Demaryius Thomas WR | 16.30 | |
| TE | David Njoku TE | 1.00 | 100% |
| FLEX | Eric Decker WR | 12.30 | 132% |
| FLEX | Isaiah Crowell RB | 8.30 | |
| DST | Las Vegas Raiders DST | 4.00 | 100% |
| Total | 107.3 | 88.4% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Deshaun Watson QB | 23.30 | 49.4% |
| RB | Mark Ingram RB | 27.50 | 100% |
| RB | Matt Breida RB | 4.60 | |
| WR | Antonio Brown WR | 25.50 | 86.9% |
| WR | Michael Crabtree WR | 14.20 | |
| TE | Benjamin Watson TE | 5.80 | 58.6% |
| FLEX | Robby Anderson WR | 9.60 | 96.8% |
| FLEX | Jordy Nelson WR | 9.00 | |
| DST | Washington Commanders DST | 5.00 | 100% |
| Total | 124.5 | 83.9% | |