| Starters | ||
| Pos | Player | Points |
| QB | Deshaun Watson QB | 28.10 |
| RB | Tevin Coleman RB | 0.60 |
| RB | Chris Carson RB | 10.60 |
| WR | Amari Cooper WR | 17.30 |
| WR | Chris Godwin WR | 12.60 |
| TE | Mark Andrews TE | 1.90 |
| FLEX | Keenan Allen WR | 10.80 |
| FLEX | Julian Edelman WR | 20.30 |
| DST | New York Jets DST | 4.00 |
| Total | 106.2 | |
| Starters | ||
| Pos | Player | Points |
| Total | 0 | |
| Bench | ||
| Pos | Player | Points |
| BN | Will Fuller WR | |
| BN | Dallas Cowboys DST | 5.00 |
| BN | Emmanuel Sanders WR | 30.60 |
| BN | Lamar Miller RB | |
| BN | Matthew Stafford QB | |
| BN | Joe Mixon RB | 26.10 |
| BN | Ryan Tannehill QB | 27.50 |
| BN | Ito Smith RB | |
| BN | Michael Gallup WR | 13.90 |
| BN | Hollywood Brown WR | 1.30 |
| Bench | ||
| Pos | Player | Points |
| BN | Julio Jones WR | 9.10 |
| BN | James White RB | 9.90 |
| BN | Cole Beasley WR | 12.90 |
| BN | Derrick Henry RB | 23.40 |
| BN | Travis Kelce TE | 14.50 |
| BN | Taylor Gabriel WR | |
| BN | Derek Carr QB | 20.20 |
| BN | Green Bay Packers DST | 7.00 |
| BN | Adam Humphries WR | |
| BN | Jamaal Williams RB | 2.40 |
| BN | Carolina Panthers DST | -3.00 |
| BN | Austin Ekeler RB | 29.30 |
| BN | Chase Edmonds RB | 0.90 |
| BN | Dallas Goedert TE | 5.60 |
| BN | Anthony Miller WR | 11.70 |
| BN | James Washington WR | 5.30 |
| BN | Mecole Hardman WR | 11.30 |
| BN | Darrell Henderson RB | |
| BN | Gardner Minshew QB | 13.60 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Deshaun Watson QB | 28.10 | 100% |
| RB | Joe Mixon RB | 26.10 | 30.5% |
| RB | Chris Carson RB | 10.60 | |
| WR | Emmanuel Sanders WR | 30.60 | 58.7% |
| WR | Julian Edelman WR | 20.30 | |
| TE | Mark Andrews TE | 1.90 | 100% |
| FLEX | Amari Cooper WR | 17.30 | 99.7% |
| FLEX | Michael Gallup WR | 13.90 | |
| DST | Dallas Cowboys DST | 5.00 | 80% |
| Total | 153.8 | 69.1% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Derek Carr QB | 20.20 | 0% |
| RB | Austin Ekeler RB | 29.30 | 0% |
| RB | Derrick Henry RB | 23.40 | |
| WR | Cole Beasley WR | 12.90 | 0% |
| WR | Anthony Miller WR | 11.70 | |
| TE | Travis Kelce TE | 14.50 | 0% |
| FLEX | Mecole Hardman WR | 11.30 | 0% |
| FLEX | James White RB | 9.90 | |
| DST | Green Bay Packers DST | 7.00 | 0% |
| Total | 140.2 | 0% | |