| Starters | ||
| Pos | Player | Points |
| QB | Russell Wilson QB | 19.30 |
| RB | Carlos Hyde RB | 16.40 |
| RB | Alvin Kamara RB | 11.40 |
| WR | Tyler Boyd WR | 4.10 |
| WR | JuJu Smith-Schuster WR | |
| TE | Jimmy Graham TE | 0.50 |
| FLEX | Jonnu Smith TE | 14.20 |
| FLEX | Jordan Wilkins RB | 8.20 |
| DST | Philadelphia Eagles DST | 8.00 |
| Total | 82.1 | |
| Starters | ||
| Pos | Player | Points |
| QB | Baker Mayfield QB | 17.00 |
| RB | Mark Ingram RB | 23.10 |
| RB | Leonard Fournette RB | 9.80 |
| WR | Robert Woods WR | 3.70 |
| WR | Tyrell Williams WR | 11.50 |
| TE | Austin Hooper TE | 3.50 |
| FLEX | O.J. Howard TE | 6.60 |
| FLEX | Dede Westbrook WR | 3.10 |
| DST | Los Angeles Chargers DST | 1.00 |
| Total | 79.3 | |
| Bench | ||
| Pos | Player | Points |
| BN | Marqise Lee WR | |
| BN | Denver Broncos DST | 5.00 |
| BN | A.J. Green WR | |
| BN | DeSean Jackson WR | |
| BN | Javorius Allen RB | 8.80 |
| BN | Mike Davis RB | |
| BN | Jared Goff QB | 17.60 |
| BN | Kerryon Johnson RB | |
| BN | Dwayne Haskins QB | 19.00 |
| Bench | ||
| Pos | Player | Points |
| BN | Matt Ryan QB | 19.10 |
| BN | Jacksonville Jaguars DST | 5.00 |
| BN | Jalen Richard RB | 4.60 |
| BN | Alshon Jeffery WR | |
| BN | Latavius Murray RB | 5.90 |
| BN | Damien Williams RB | |
| BN | DJ Chark Jr. WR | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Russell Wilson QB | 19.30 | 100% |
| RB | Carlos Hyde RB | 16.40 | 100% |
| RB | Alvin Kamara RB | 11.40 | |
| WR | Tyler Boyd WR | 4.10 | 100% |
| WR | DeSean Jackson WR | ||
| TE | Jonnu Smith TE | 14.20 | 3.5% |
| FLEX | Javorius Allen RB | 8.80 | 131.8% |
| FLEX | Jordan Wilkins RB | 8.20 | |
| DST | Philadelphia Eagles DST | 8.00 | 100% |
| Total | 90.4 | 90.8% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Matt Ryan QB | 19.10 | 89% |
| RB | Mark Ingram RB | 23.10 | 100% |
| RB | Leonard Fournette RB | 9.80 | |
| WR | Tyrell Williams WR | 11.50 | 100% |
| WR | Robert Woods WR | 3.70 | |
| TE | O.J. Howard TE | 6.60 | 53% |
| FLEX | Latavius Murray RB | 5.90 | 92.4% |
| FLEX | Jalen Richard RB | 4.60 | |
| DST | Jacksonville Jaguars DST | 5.00 | 20% |
| Total | 89.3 | 88.8% | |