| Starters | ||
| Pos | Player | Points |
| QB | Jared Goff QB | 9.90 |
| RB | Alvin Kamara RB | 10.20 |
| RB | Kareem Hunt RB | 13.50 |
| WR | Jermaine Kearse WR | 9.90 |
| WR | JuJu Smith-Schuster WR | 5.30 |
| TE | Jordan Reed TE | 5.70 |
| FLEX | Tarik Cohen RB | 13.10 |
| FLEX | Alex Collins RB | 7.40 |
| DST | Atlanta Falcons DST | 4.00 |
| Total | 79 | |
| Starters | ||
| Pos | Player | Points |
| QB | Matthew Stafford QB | 14.90 |
| RB | Leonard Fournette RB | 20.80 |
| RB | Duke Johnson RB | 5.40 |
| WR | DeAndre Hopkins WR | 8.90 |
| WR | Randall Cobb WR | 4.30 |
| TE | Rob Gronkowski TE | 23.30 |
| FLEX | C.J. Anderson RB | 1.70 |
| FLEX | Devin Funchess TE | 5.10 |
| DST | Houston Texans DST | 23.00 |
| Total | 107.4 | |
| Bench | ||
| Pos | Player | Points |
| BN | Russell Wilson QB | 0.00 |
| BN | Tyrod Taylor QB | 0.00 |
| BN | Thomas Rawls RB | 0.00 |
| BN | Giovani Bernard RB | 0.00 |
| BN | A.J. Green WR | 0.00 |
| BN | Doug Baldwin WR | 0.00 |
| BN | Sterling Shepard WR | 0.00 |
| BN | Charles Clay TE | 0.00 |
| BN | San Francisco 49ers DST | 2.00 |
| BN | Adrian Peterson RB | 25.40 |
| Bench | ||
| Pos | Player | Points |
| BN | DeVante Parker WR | 0.00 |
| BN | Mike Williams WR | 2.00 |
| BN | Marqise Lee WR | 12.50 |
| BN | Kenny Golladay WR | 0.00 |
| BN | Paul Richardson WR | 0.00 |
| BN | Chicago Bears DST | 17.00 |
| BN | Will Fuller WR | 15.10 |
| BN | Ed Dickson TE | 5.60 |
| BN | Rashard Higgins WR | 1.80 |
| BN | Kevin Hogan QB | 7.20 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Jared Goff QB | 9.90 | 100% |
| RB | Adrian Peterson RB | 25.40 | 60.9% |
| RB | Kareem Hunt RB | 13.50 | |
| WR | Jermaine Kearse WR | 9.90 | 100% |
| WR | JuJu Smith-Schuster WR | 5.30 | |
| TE | Jordan Reed TE | 5.70 | 100% |
| FLEX | Tarik Cohen RB | 13.10 | 88% |
| FLEX | Alvin Kamara RB | 10.20 | |
| DST | Atlanta Falcons DST | 4.00 | 100% |
| Total | 97 | 81.4% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Matthew Stafford QB | 14.90 | 100% |
| RB | Leonard Fournette RB | 20.80 | 100% |
| RB | Duke Johnson RB | 5.40 | |
| WR | Will Fuller WR | 15.10 | 47.8% |
| WR | Marqise Lee WR | 12.50 | |
| TE | Rob Gronkowski TE | 23.30 | 100% |
| FLEX | DeAndre Hopkins WR | 8.90 | 46.9% |
| FLEX | Ed Dickson TE | 5.60 | |
| DST | Houston Texans DST | 23.00 | 100% |
| Total | 129.5 | 82.9% | |