| Starters | ||
| Pos | Player | Points |
| Total | 0 | |
| Starters | ||
| Pos | Player | Points |
| Total | 0 | |
| Bench | ||
| Pos | Player | Points |
| BN | Peyton Barber RB | 1.50 |
| BN | Tom Brady QB | 18.64 |
| BN | Jacksonville Jaguars DST | -2.00 |
| BN | Jordan Howard RB | |
| BN | Kenyan Drake RB | 28.40 |
| BN | Allen Robinson WR | 7.80 |
| BN | Hunter Henry TE | |
| BN | Mike Evans WR | 1.50 |
| BN | New England Patriots DST | 8.00 |
| BN | Dalvin Cook RB | |
| BN | Hayden Hurst TE | 13.70 |
| BN | Auden Tate WR | |
| BN | Marquez Valdes-Scantling WR | 4.70 |
| BN | Kyler Murray QB | 32.92 |
| BN | Drew Lock QB | -0.54 |
| BN | Alexander Mattison RB | 3.50 |
| BN | NKeal Harry TE | 0.00 |
| BN | KeShawn Vaughn RB | 4.20 |
| BN | K.J. Hamler WR | |
| Bench | ||
| Pos | Player | Points |
| BN | Rex Burkhead RB | 1.40 |
| BN | Los Angeles Rams DST | -1.00 |
| BN | Frank Gore RB | 9.00 |
| BN | Jarvis Landry WR | 5.50 |
| BN | Golden Tate WR | 1.60 |
| BN | San Francisco 49ers DST | 5.00 |
| BN | George Kittle TE | 20.40 |
| BN | Mike Williams WR | |
| BN | Chris Godwin WR | 7.30 |
| BN | Mo Alie-Cox TE | |
| BN | A.J. Brown WR | 20.30 |
| BN | Irv Smith Jr. TE | 9.50 |
| BN | David Montgomery RB | 11.70 |
| BN | Robert Tonyan TE | 4.00 |
| BN | Joe Burrow QB | 14.72 |
| BN | Jerry Jeudy WR | 4.20 |
| BN | Chase Claypool WR | 16.10 |
| BN | Van Jefferson WR | 1.30 |
| BN | Lamical Perine RB | 4.60 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Kyler Murray QB | 32.92 | 0% |
| RB | Kenyan Drake RB | 28.40 | 0% |
| RB | KeShawn Vaughn RB | 4.20 | |
| WR | Randall Cobb WR | 9.20 | 0% |
| WR | Allen Robinson WR | 7.80 | |
| TE | Hayden Hurst TE | 13.70 | 0% |
| FLEX | Marquez Valdes-Scantling WR | 4.70 | 0% |
| FLEX | Alexander Mattison RB | 3.50 | |
| DST | New England Patriots DST | 8.00 | 0% |
| Total | 112.42 | 0% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Joe Burrow QB | 14.72 | 0% |
| RB | David Montgomery RB | 11.70 | 0% |
| RB | Frank Gore RB | 9.00 | |
| WR | A.J. Brown WR | 20.30 | 0% |
| WR | Chase Claypool WR | 16.10 | |
| TE | George Kittle TE | 20.40 | 0% |
| FLEX | Irv Smith Jr. TE | 9.50 | 0% |
| FLEX | Chris Godwin WR | 7.30 | |
| DST | San Francisco 49ers DST | 5.00 | 0% |
| Total | 114.02 | 0% | |