| Starters | ||
| Pos | Player | Points |
| QB | Matt Ryan QB | 15.94 |
| RB | Jerick McKinnon RB | 12.90 |
| RB | Leonard Fournette RB | 8.60 |
| WR | Robert Woods WR | 24.90 |
| WR | Justin Jefferson WR | 4.10 |
| TE | Cole Kmet TE | 0.70 |
| FLEX | Zack Moss RB | 20.10 |
| FLEX | Jonathan Taylor RB | 4.10 |
| DST | Kansas City Chiefs DST | 10.00 |
| Total | 101.34 | |
| Starters | ||
| Pos | Player | Points |
| QB | Drew Brees QB | 23.60 |
| RB | Ronald Jones II RB | 4.60 |
| RB | Josh Jacobs RB | 12.90 |
| WR | Diontae Johnson WR | 1.10 |
| WR | D.K. Metcalf WR | 34.10 |
| TE | T.J. Hockenson TE | 10.00 |
| FLEX | Giovani Bernard RB | 21.30 |
| FLEX | CeeDee Lamb WR | 6.80 |
| DST | Tampa Bay Buccaneers DST | 6.00 |
| Total | 120.4 | |
| Bench | ||
| Pos | Player | Points |
| BN | Mark Ingram RB | 0.00 |
| BN | Cam Newton QB | 18.36 |
| BN | Alshon Jeffery WR | 0.00 |
| BN | Tyrell Williams WR | 0.00 |
| BN | Austin Hooper TE | 0.00 |
| BN | O.J. Howard TE | 0.00 |
| BN | Dede Westbrook WR | 0.00 |
| BN | Cordarrelle Patterson RB | 3.70 |
| BN | New Orleans Saints DST | 7.00 |
| BN | Baker Mayfield QB | 7.78 |
| BN | DJ Chark Jr. WR | 0.00 |
| Bench | ||
| Pos | Player | Points |
| BN | DeAndre Hopkins WR | 0.00 |
| BN | Antonio Brown WR | 0.00 |
| BN | Deshaun Watson QB | 0.00 |
| BN | Joe Mixon RB | 0.00 |
| BN | Chris Carson RB | 0.00 |
| BN | Tim Patrick WR | 0.00 |
| BN | DeeJay Dallas RB | 20.30 |
| BN | Eno Benjamin RB | 0.00 |
| BN | Laviska Shenault Jr. WR | 0.00 |
| BN | Tua Tagovailoa QB | 7.72 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Cam Newton QB | 18.36 | 86.8% |
| RB | Zack Moss RB | 20.10 | 65.2% |
| RB | Jerick McKinnon RB | 12.90 | |
| WR | Robert Woods WR | 24.90 | 100% |
| WR | Justin Jefferson WR | 4.10 | |
| TE | Cole Kmet TE | 0.70 | 100% |
| FLEX | Leonard Fournette RB | 8.60 | 190.6% |
| FLEX | Jonathan Taylor RB | 4.10 | |
| DST | Kansas City Chiefs DST | 10.00 | 100% |
| Total | 103.76 | 97.7% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Drew Brees QB | 23.60 | 100% |
| RB | Giovani Bernard RB | 21.30 | 42.1% |
| RB | DeeJay Dallas RB | 20.30 | |
| WR | D.K. Metcalf WR | 34.10 | 86.1% |
| WR | CeeDee Lamb WR | 6.80 | |
| TE | T.J. Hockenson TE | 10.00 | 100% |
| FLEX | Josh Jacobs RB | 12.90 | 160.6% |
| FLEX | Ronald Jones II RB | 4.60 | |
| DST | Tampa Bay Buccaneers DST | 6.00 | 100% |
| Total | 139.6 | 86.2% | |