| Starters | ||
| Pos | Player | Points |
| QB | Lamar Jackson QB | 20.00 |
| RB | DAndre Swift RB | 20.40 |
| RB | James Robinson RB | 6.90 |
| WR | D.J. Moore WR | 12.85 |
| WR | Terry McLaurin WR | 8.20 |
| TE | Rob Gronkowski TE | 25.00 |
| FLEX | Hollywood Brown WR | 16.40 |
| FLEX | Brandon Aiyuk WR | 0.35 |
| DST | Miami Dolphins DST | 4.00 |
| Total | 114.1 | |
| Starters | ||
| Pos | Player | Points |
| QB | Russell Wilson QB | 35.06 |
| RB | Kenyan Drake RB | 9.50 |
| RB | Jonathan Taylor RB | 14.60 |
| WR | Robert Woods WR | 10.90 |
| WR | Justin Jefferson WR | 10.04 |
| TE | Hunter Henry TE | 4.60 |
| FLEX | Tevin Coleman RB | 2.40 |
| FLEX | DeVonta Smith WR | 16.10 |
| DST | San Francisco 49ers DST | 7.00 |
| Total | 110.2 | |
| Bench | ||
| Pos | Player | Points |
| BN | Giovani Bernard RB | 2.20 |
| BN | David Johnson RB | 10.30 |
| BN | Washington Commanders DST | 1.00 |
| BN | Deshaun Watson QB | 0.00 |
| BN | Evan Engram TE | 0.00 |
| BN | Kenny Golladay WR | 8.40 |
| BN | Michael Gallup WR | 5.60 |
| BN | Blake Jarwin TE | 3.50 |
| BN | JaMarr Chase WR | 18.40 |
| BN | Javonte Williams RB | 4.60 |
| Bench | ||
| Pos | Player | Points |
| BN | Will Fuller WR | 0.00 |
| BN | Latavius Murray RB | 8.80 |
| BN | New Orleans Saints DST | 14.00 |
| BN | Baker Mayfield QB | 10.64 |
| BN | DJ Chark Jr. WR | 16.10 |
| BN | Zack Moss RB | 0.00 |
| BN | Cole Kmet TE | 6.70 |
| BN | Josh Palmer WR | 2.20 |
| BN | Pat Freiermuth TE | 2.90 |
| BN | Justin Fields QB | 6.70 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Lamar Jackson QB | 20.00 | 100% |
| RB | DAndre Swift RB | 20.40 | 88.9% |
| RB | David Johnson RB | 10.30 | |
| WR | JaMarr Chase WR | 18.40 | 60.5% |
| WR | Hollywood Brown WR | 16.40 | |
| TE | Rob Gronkowski TE | 25.00 | 100% |
| FLEX | D.J. Moore WR | 12.85 | 78.8% |
| FLEX | Kenny Golladay WR | 8.40 | |
| DST | Miami Dolphins DST | 4.00 | 100% |
| Total | 135.75 | 84.1% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Russell Wilson QB | 35.06 | 100% |
| RB | Jonathan Taylor RB | 14.60 | 100% |
| RB | Kenyan Drake RB | 9.50 | |
| WR | DeVonta Smith WR | 16.10 | 65% |
| WR | DJ Chark Jr. WR | 16.10 | |
| TE | Cole Kmet TE | 6.70 | 68.7% |
| FLEX | Robert Woods WR | 10.90 | 88.3% |
| FLEX | Justin Jefferson WR | 10.04 | |
| DST | New Orleans Saints DST | 14.00 | 50% |
| Total | 133 | 82.9% | |