| Starters | ||
| Pos | Player | Points |
| QB | Aaron Rodgers QB | -2.68 |
| RB | Ezekiel Elliott RB | 4.90 |
| RB | Alvin Kamara RB | 16.60 |
| WR | Chris Godwin WR | 19.00 |
| WR | A.J. Brown WR | 12.90 |
| TE | George Kittle TE | 9.80 |
| FLEX | Nick Chubb RB | 21.10 |
| FLEX | David Montgomery RB | 18.30 |
| DST | Los Angeles Rams DST | 8.00 |
| Total | 107.92 | |
| Starters | ||
| Pos | Player | Points |
| QB | Teddy Bridgewater QB | 24.46 |
| RB | Derrick Henry RB | 9.20 |
| RB | Austin Ekeler RB | 11.70 |
| WR | Julio Jones WR | 20.20 |
| WR | Mecole Hardman WR | 3.75 |
| TE | Travis Kelce TE | 22.60 |
| FLEX | Chase Edmonds RB | 12.60 |
| FLEX | Darrell Henderson RB | 15.20 |
| DST | Los Angeles Chargers DST | 6.00 |
| Total | 125.71 | |
| Bench | ||
| Pos | Player | Points |
| BN | Kansas City Chiefs DST | 0.00 |
| BN | Mike Williams WR | 18.20 |
| BN | Saquon Barkley RB | 3.20 |
| BN | Courtland Sutton WR | 1.90 |
| BN | Robert Tonyan TE | 1.80 |
| BN | Denzel Mims WR | 4.50 |
| BN | Lamical Perine RB | 0.00 |
| BN | Gabriel Davis WR | 11.00 |
| BN | Zach Wilson QB | 20.32 |
| Bench | ||
| Pos | Player | Points |
| BN | James White RB | 9.10 |
| BN | Cole Beasley WR | 10.00 |
| BN | Jamaal Williams RB | 21.00 |
| BN | Mike Gesicki TE | 0.00 |
| BN | Dallas Goedert TE | 12.20 |
| BN | Allen Lazard WR | 2.60 |
| BN | Taysom Hill TE | 0.22 |
| BN | Darrynton Evans RB | 0.00 |
| BN | Cam Akers RB | 0.00 |
| BN | Amon-Ra St. Brown WR | 3.30 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Zach Wilson QB | 20.32 | -13.2% |
| RB | Nick Chubb RB | 21.10 | 54.6% |
| RB | David Montgomery RB | 18.30 | |
| WR | Chris Godwin WR | 19.00 | 85.8% |
| WR | Mike Williams WR | 18.20 | |
| TE | George Kittle TE | 9.80 | 100% |
| FLEX | Alvin Kamara RB | 16.60 | 133.6% |
| FLEX | A.J. Brown WR | 12.90 | |
| DST | Los Angeles Rams DST | 8.00 | 100% |
| Total | 144.22 | 74.8% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Teddy Bridgewater QB | 24.46 | 100% |
| RB | Jamaal Williams RB | 21.00 | 57.7% |
| RB | Darrell Henderson RB | 15.20 | |
| WR | Julio Jones WR | 20.20 | 79.3% |
| WR | Cole Beasley WR | 10.00 | |
| TE | Travis Kelce TE | 22.60 | 100% |
| FLEX | Chase Edmonds RB | 12.60 | 112.1% |
| FLEX | Dallas Goedert TE | 12.20 | |
| DST | Los Angeles Chargers DST | 6.00 | 100% |
| Total | 144.26 | 87.1% | |