| Starters | ||
| Pos | Player | Points |
| QB | Matt Ryan QB | 7.36 |
| RB | Joe Mixon RB | 23.00 |
| RB | Josh Jacobs RB | 16.50 |
| WR | DeAndre Hopkins WR | 23.30 |
| WR | D.K. Metcalf WR | 14.00 |
| TE | T.J. Hockenson TE | 21.70 |
| FLEX | Diontae Johnson WR | 12.10 |
| FLEX | CeeDee Lamb WR | 20.50 |
| DST | Tampa Bay Buccaneers DST | -3.00 |
| Total | 135.46 | |
| Starters | ||
| Pos | Player | Points |
| QB | Josh Allen QB | 19.20 |
| RB | Aaron Jones RB | 3.20 |
| RB | Christian McCaffrey RB | 23.20 |
| WR | Amari Cooper WR | 32.40 |
| WR | Davante Adams WR | 8.10 |
| TE | Logan Thomas TE | 10.50 |
| FLEX | Keenan Allen WR | 14.50 |
| FLEX | Marvin Jones WR | 16.20 |
| DST | Seattle Seahawks DST | 6.00 |
| Total | 133.3 | |
| Bench | ||
| Pos | Player | Points |
| BN | Mark Ingram RB | 14.50 |
| BN | Antonio Brown WR | 21.20 |
| BN | Melvin Gordon RB | 19.30 |
| BN | Green Bay Packers DST | -3.00 |
| BN | Malcolm Brown RB | 1.60 |
| BN | Phillip Lindsay RB | 8.50 |
| BN | DeeJay Dallas RB | 2.60 |
| BN | Bryan Edwards WR | 10.10 |
| BN | Laviska Shenault Jr. WR | 9.40 |
| BN | Tua Tagovailoa QB | 16.18 |
| Bench | ||
| Pos | Player | Points |
| BN | Sterling Shepard WR | 20.80 |
| BN | Pittsburgh Steelers DST | 13.00 |
| BN | Jamison Crowder WR | 0.00 |
| BN | Carson Wentz QB | 22.34 |
| BN | Kirk Cousins QB | 26.04 |
| BN | Leonard Fournette RB | 8.40 |
| BN | James Conner RB | 5.30 |
| BN | Anthony Firkser TE | 3.40 |
| BN | Salvon Ahmed RB | 3.80 |
| BN | Marquez Callaway WR | 1.90 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Tua Tagovailoa QB | 16.18 | 45.5% |
| RB | Joe Mixon RB | 23.00 | 93.4% |
| RB | Melvin Gordon RB | 19.30 | |
| WR | DeAndre Hopkins WR | 23.30 | 83.8% |
| WR | Antonio Brown WR | 21.20 | |
| TE | T.J. Hockenson TE | 21.70 | 100% |
| FLEX | CeeDee Lamb WR | 20.50 | 88.1% |
| FLEX | Josh Jacobs RB | 16.50 | |
| DST | Tampa Bay Buccaneers DST | -3.00 | -- |
| Total | 158.68 | 85.4% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Kirk Cousins QB | 26.04 | 73.7% |
| RB | Christian McCaffrey RB | 23.20 | 66.7% |
| RB | Elijah Mitchell RB | 16.40 | |
| WR | Amari Cooper WR | 32.40 | 76.1% |
| WR | Sterling Shepard WR | 20.80 | |
| TE | Logan Thomas TE | 10.50 | 100% |
| FLEX | Marvin Jones WR | 16.20 | 100% |
| FLEX | Keenan Allen WR | 14.50 | |
| DST | Pittsburgh Steelers DST | 13.00 | 46.2% |
| Total | 173.04 | 77% | |