| Starters | ||
| Pos | Player | Points |
| QB | Trevor Lawrence QB | 19.08 |
| RB | Kareem Hunt RB | 15.60 |
| RB | Myles Gaskin RB | 10.10 |
| WR | DeVante Parker WR | 10.10 |
| WR | Corey Davis WR | 24.20 |
| TE | Darren Waller TE | 21.50 |
| FLEX | Raheem Mostert RB | 2.00 |
| FLEX | Damien Harris RB | 10.70 |
| DST | Minnesota Vikings DST | 4.00 |
| Total | 117.28 | |
| Starters | ||
| Pos | Player | Points |
| QB | Justin Herbert QB | 13.38 |
| RB | Marlon Mack RB | 0.00 |
| RB | Clyde Edwards-Helaire RB | 8.70 |
| WR | Robby Anderson WR | 12.20 |
| WR | JuJu Smith-Schuster WR | 7.20 |
| TE | Kyle Pitts TE | 5.10 |
| FLEX | Tyler Boyd WR | 4.70 |
| FLEX | Jerry Jeudy WR | 10.20 |
| DST | Denver Broncos DST | 7.00 |
| Total | 68.48 | |
| Bench | ||
| Pos | Player | Points |
| BN | New York Giants DST | 1.00 |
| BN | Nelson Agholor WR | 15.70 |
| BN | Michael Thomas WR | 0.00 |
| BN | Ty Johnson RB | 3.10 |
| BN | Parris Campbell WR | 2.90 |
| BN | Noah Fant TE | 9.20 |
| BN | Joe Burrow QB | 22.64 |
| BN | A.J. Dillon RB | 3.10 |
| BN | Darnell Mooney WR | 5.10 |
| BN | Jaylen Waddle WR | 14.10 |
| Bench | ||
| Pos | Player | Points |
| BN | Eric Ebron TE | 2.40 |
| BN | Sammy Watkins WR | 11.60 |
| BN | Brandin Cooks WR | 15.70 |
| BN | Antonio Gandy-Golden TE | 0.00 |
| BN | Joshua Kelley RB | 0.00 |
| BN | Jalen Reagor WR | 14.85 |
| BN | Javian Hawkins RB | 0.00 |
| BN | Jermar Jefferson RB | 0.00 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Joe Burrow QB | 22.64 | 84.3% |
| RB | Kareem Hunt RB | 15.60 | 97.7% |
| RB | Damien Harris RB | 10.70 | |
| WR | Corey Davis WR | 24.20 | 86% |
| WR | Nelson Agholor WR | 15.70 | |
| TE | Darren Waller TE | 21.50 | 100% |
| FLEX | Jaylen Waddle WR | 14.10 | 50.4% |
| FLEX | Rondale Moore WR | 11.10 | |
| DST | Minnesota Vikings DST | 4.00 | 100% |
| Total | 139.54 | 84% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Jared Goff QB | 32.92 | 40.6% |
| RB | Clyde Edwards-Helaire RB | 8.70 | 100% |
| RB | Javian Hawkins RB | 0.00 | |
| WR | Brandin Cooks WR | 15.70 | 63.5% |
| WR | Jalen Reagor WR | 14.85 | |
| TE | Kyle Pitts TE | 5.10 | 100% |
| FLEX | Robby Anderson WR | 12.20 | 62.6% |
| FLEX | Sammy Watkins WR | 11.60 | |
| DST | Denver Broncos DST | 7.00 | 100% |
| Total | 108.07 | 63.4% | |