| Starters | ||
| Pos | Player | Points |
| QB | Joe Burrow QB | 8.28 |
| RB | Kareem Hunt RB | 5.80 |
| RB | Myles Gaskin RB | 6.60 |
| WR | DeVante Parker WR | 6.70 |
| WR | Corey Davis WR | 1.80 |
| TE | Darren Waller TE | 9.00 |
| FLEX | Damien Harris RB | 12.90 |
| FLEX | Darnell Mooney WR | 10.10 |
| DST | Carolina Panthers DST | 14.00 |
| Total | 75.18 | |
| Starters | ||
| Pos | Player | Points |
| QB | Dak Prescott QB | 5.48 |
| RB | Chris Carson RB | 15.10 |
| RB | Tony Pollard RB | 25.05 |
| WR | Allen Robinson WR | 9.40 |
| WR | Tee Higgins WR | 13.00 |
| TE | Tyler Higbee TE | 1.30 |
| FLEX | Tyler Lockett WR | 27.80 |
| FLEX | Adam Thielen WR | 12.90 |
| DST | Buffalo Bills DST | 19.00 |
| Total | 129.03 | |
| Bench | ||
| Pos | Player | Points |
| BN | Minnesota Vikings DST | 7.00 |
| BN | Philadelphia Eagles DST | 1.00 |
| BN | Nelson Agholor WR | 3.60 |
| BN | Michael Thomas WR | 0.00 |
| BN | Ty Johnson RB | 5.00 |
| BN | Parris Campbell WR | 0.00 |
| BN | Noah Fant TE | 11.30 |
| BN | A.J. Dillon RB | 3.10 |
| BN | Trevor Lawrence QB | 4.82 |
| BN | Jaylen Waddle WR | 5.80 |
| Bench | ||
| Pos | Player | Points |
| BN | Ben Roethlisberger QB | 13.80 |
| BN | Wayne Gallman RB | 0.00 |
| BN | Curtis Samuel WR | 0.00 |
| BN | Sam Darnold QB | 20.90 |
| BN | Rashaad Penny RB | 0.00 |
| BN | Justin Jackson RB | 3.40 |
| BN | Darius Slayton WR | 12.90 |
| BN | Tim Patrick WR | 11.20 |
| BN | Darrel Williams RB | 5.80 |
| BN | Michael Pittman Jr. WR | 16.30 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Joe Burrow QB | 8.28 | 100% |
| RB | Damien Harris RB | 12.90 | 63.6% |
| RB | Myles Gaskin RB | 6.60 | |
| WR | Rondale Moore WR | 22.90 | 25.8% |
| WR | Darnell Mooney WR | 10.10 | |
| TE | Noah Fant TE | 11.30 | 79.6% |
| FLEX | Darren Waller TE | 9.00 | 146.5% |
| FLEX | DeVante Parker WR | 6.70 | |
| DST | Carolina Panthers DST | 14.00 | 100% |
| Total | 101.78 | 73.9% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Sam Darnold QB | 20.90 | 26.2% |
| RB | Tony Pollard RB | 25.05 | 100% |
| RB | Chris Carson RB | 15.10 | |
| WR | Tyler Lockett WR | 27.80 | 50.8% |
| WR | Michael Pittman Jr. WR | 16.30 | |
| TE | Juwan Johnson TE | 2.80 | 46.4% |
| FLEX | Tee Higgins WR | 13.00 | 157.1% |
| FLEX | Adam Thielen WR | 12.90 | |
| DST | Buffalo Bills DST | 19.00 | 100% |
| Total | 152.85 | 84.4% | |