| Starters | ||
| Pos | Player | Points |
| QB | Marcus Mariota QB | 8.90 |
| RB | Dion Lewis RB | 9.40 |
| RB | Jerick McKinnon RB | 7.20 |
| WR | Kelvin Benjamin WR | 8.00 |
| WR | Pierre Garcon WR | 7.40 |
| TE | Evan Engram TE | 15.00 |
| FLEX | Latavius Murray RB | 17.30 |
| FLEX | Chris Hogan WR | 9.10 |
| DST | Pittsburgh Steelers DST | 12.00 |
| Total | 94.3 | |
| Starters | ||
| Pos | Player | Points |
| QB | Russell Wilson QB | 26.40 |
| RB | Alvin Kamara RB | 13.20 |
| RB | Kareem Hunt RB | 13.70 |
| WR | A.J. Green WR | 5.60 |
| WR | Doug Baldwin WR | 19.70 |
| TE | Jordan Reed TE | 22.40 |
| FLEX | Adrian Peterson RB | 3.80 |
| FLEX | Tarik Cohen RB | 8.10 |
| DST | San Francisco 49ers DST | -9.00 |
| Total | 103.9 | |
| Bench | ||
| Pos | Player | Points |
| BN | Arizona Cardinals DST | -1.00 |
| BN | Tyrell Williams WR | 1.60 |
| BN | Charcandrick West RB | 0.00 |
| BN | Carson Palmer QB | 2.90 |
| BN | Ed Dickson TE | 3.30 |
| BN | Chris Johnson RB | 0.00 |
| BN | Trevor Siemian QB | 5.70 |
| BN | Kerwynn Williams RB | 6.50 |
| BN | J.J. Nelson WR | 4.90 |
| Bench | ||
| Pos | Player | Points |
| BN | Sterling Shepard WR | 0.00 |
| BN | Thomas Rawls RB | 3.70 |
| BN | Giovani Bernard RB | 1.20 |
| BN | Tyrod Taylor QB | 20.00 |
| BN | Atlanta Falcons DST | -1.00 |
| BN | Charles Clay TE | 0.00 |
| BN | Alex Collins RB | 3.00 |
| BN | Jared Goff QB | 18.70 |
| BN | Jermaine Kearse WR | 9.40 |
| BN | JuJu Smith-Schuster WR | 10.90 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Marcus Mariota QB | 8.90 | 100% |
| RB | Latavius Murray RB | 17.30 | 62.2% |
| RB | Dion Lewis RB | 9.40 | |
| WR | Chris Hogan WR | 9.10 | 90.1% |
| WR | Kelvin Benjamin WR | 8.00 | |
| TE | Evan Engram TE | 15.00 | 100% |
| FLEX | Pierre Garcon WR | 7.40 | 180.8% |
| FLEX | Jerick McKinnon RB | 7.20 | |
| DST | Pittsburgh Steelers DST | 12.00 | 100% |
| Total | 94.3 | 100% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Russell Wilson QB | 26.40 | 100% |
| RB | Kareem Hunt RB | 13.70 | 100% |
| RB | Alvin Kamara RB | 13.20 | |
| WR | Doug Baldwin WR | 19.70 | 82.7% |
| WR | JuJu Smith-Schuster WR | 10.90 | |
| TE | Jordan Reed TE | 22.40 | 100% |
| FLEX | Jermaine Kearse WR | 9.40 | 68% |
| FLEX | Tarik Cohen RB | 8.10 | |
| DST | Atlanta Falcons DST | -1.00 | -- |
| Total | 122.8 | 84.6% | |