| Starters | ||
| Pos | Player | Points |
| QB | Josh Allen QB | 45.22 |
| RB | Aaron Jones RB | 16.60 |
| RB | Christian McCaffrey RB | 5.00 |
| WR | Amari Cooper WR | 4.10 |
| WR | Davante Adams WR | 25.20 |
| TE | Logan Thomas TE | 10.20 |
| FLEX | Keenan Allen WR | 15.00 |
| FLEX | Marvin Jones WR | 9.20 |
| DST | Pittsburgh Steelers DST | 4.00 |
| Total | 134.52 | |
| Starters | ||
| Pos | Player | Points |
| QB | Russell Wilson QB | 18.62 |
| RB | Kenyan Drake RB | 7.20 |
| RB | Jonathan Taylor RB | 7.70 |
| WR | Robert Woods WR | 5.30 |
| WR | Justin Jefferson WR | 22.30 |
| TE | Cole Kmet TE | 1.60 |
| FLEX | Latavius Murray RB | 2.80 |
| FLEX | DeVonta Smith WR | 4.30 |
| DST | New Orleans Saints DST | 19.00 |
| Total | 88.82 | |
| Bench | ||
| Pos | Player | Points |
| BN | Sterling Shepard WR | 2.60 |
| BN | Jamison Crowder WR | 0.00 |
| BN | Seattle Seahawks DST | -5.00 |
| BN | Kirk Cousins QB | 31.12 |
| BN | Leonard Fournette RB | 4.90 |
| BN | James Conner RB | 17.80 |
| BN | Daniel Jones QB | 16.54 |
| BN | Salvon Ahmed RB | 0.00 |
| BN | Marquez Callaway WR | 12.10 |
| BN | Elijah Mitchell RB | 0.00 |
| Bench | ||
| Pos | Player | Points |
| BN | Will Fuller WR | 5.50 |
| BN | Tevin Coleman RB | 0.00 |
| BN | Hunter Henry TE | 6.10 |
| BN | San Francisco 49ers DST | -1.00 |
| BN | Baker Mayfield QB | 18.94 |
| BN | DJ Chark Jr. WR | 12.40 |
| BN | Zack Moss RB | 16.60 |
| BN | Josh Palmer WR | 0.00 |
| BN | Pat Freiermuth TE | 9.70 |
| BN | Justin Fields QB | 3.92 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Josh Allen QB | 45.22 | 100% |
| RB | James Conner RB | 17.80 | 62.8% |
| RB | Aaron Jones RB | 16.60 | |
| WR | Davante Adams WR | 25.20 | 72.9% |
| WR | Keenan Allen WR | 15.00 | |
| TE | Logan Thomas TE | 10.20 | 100% |
| FLEX | Marquez Callaway WR | 12.10 | 113.6% |
| FLEX | Marvin Jones WR | 9.20 | |
| DST | Pittsburgh Steelers DST | 4.00 | 100% |
| Total | 155.32 | 86.6% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Baker Mayfield QB | 18.94 | 98.3% |
| RB | Zack Moss RB | 16.60 | 61.3% |
| RB | Jonathan Taylor RB | 7.70 | |
| WR | Justin Jefferson WR | 22.30 | 79.5% |
| WR | DJ Chark Jr. WR | 12.40 | |
| TE | Pat Freiermuth TE | 9.70 | 16.5% |
| FLEX | Kenyan Drake RB | 7.20 | 53.4% |
| FLEX | Hunter Henry TE | 6.10 | |
| DST | New Orleans Saints DST | 19.00 | 100% |
| Total | 119.94 | 74.1% | |