| Starters | ||
| Pos | Player | Points |
| QB | Dak Prescott QB | 26.12 |
| RB | Chris Carson RB | 15.20 |
| RB | Tony Pollard RB | 7.00 |
| WR | Allen Robinson WR | 3.70 |
| WR | Darius Slayton WR | 1.30 |
| TE | Tyler Higbee TE | 12.50 |
| FLEX | Tyler Lockett WR | 5.10 |
| FLEX | Adam Thielen WR | 14.00 |
| DST | Buffalo Bills DST | 9.00 |
| Total | 93.92 | |
| Starters | ||
| Pos | Player | Points |
| QB | Justin Herbert QB | 38.84 |
| RB | Marlon Mack RB | 0.00 |
| RB | Clyde Edwards-Helaire RB | 15.90 |
| WR | JuJu Smith-Schuster WR | 4.00 |
| WR | Jalen Reagor WR | 7.70 |
| TE | Kyle Pitts TE | 4.50 |
| FLEX | Tyler Boyd WR | 11.60 |
| FLEX | Brandin Cooks WR | 16.20 |
| DST | Denver Broncos DST | 17.00 |
| Total | 115.74 | |
| Bench | ||
| Pos | Player | Points |
| BN | Ben Roethlisberger QB | 11.22 |
| BN | Wayne Gallman RB | 0.00 |
| BN | Sam Darnold QB | 25.26 |
| BN | Rashaad Penny RB | 0.00 |
| BN | Justin Jackson RB | 0.00 |
| BN | Tim Patrick WR | 12.30 |
| BN | Darrel Williams RB | 4.90 |
| BN | Tee Higgins WR | 0.00 |
| BN | Michael Pittman Jr. WR | 10.30 |
| Bench | ||
| Pos | Player | Points |
| BN | Eric Ebron TE | 0.00 |
| BN | Sammy Watkins WR | 8.80 |
| BN | Robby Anderson WR | 1.30 |
| BN | Antonio Gandy-Golden TE | 0.00 |
| BN | Joshua Kelley RB | 0.00 |
| BN | Javian Hawkins RB | 0.00 |
| BN | Jermar Jefferson RB | 0.00 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Dak Prescott QB | 26.12 | 100% |
| RB | Chris Carson RB | 15.20 | 90.2% |
| RB | Chuba Hubbard RB | 9.40 | |
| WR | Adam Thielen WR | 14.00 | 19% |
| WR | Tim Patrick WR | 12.30 | |
| TE | Tyler Higbee TE | 12.50 | 100% |
| FLEX | Michael Pittman Jr. WR | 10.30 | 107.6% |
| FLEX | Demetric Felton RB | 7.45 | |
| DST | Buffalo Bills DST | 9.00 | 100% |
| Total | 116.27 | 80.8% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Justin Herbert QB | 38.84 | 100% |
| RB | Clyde Edwards-Helaire RB | 15.90 | 100% |
| RB | Jermar Jefferson RB | 0.00 | |
| WR | Brandin Cooks WR | 16.20 | 39.1% |
| WR | A.J. Green WR | 13.70 | |
| TE | Kyle Pitts TE | 4.50 | 100% |
| FLEX | Tyler Boyd WR | 11.60 | 136.3% |
| FLEX | Sammy Watkins WR | 8.80 | |
| DST | Denver Broncos DST | 17.00 | 100% |
| Total | 126.54 | 91.5% | |