| Starters | ||
| Pos | Player | Points |
| QB | Teddy Bridgewater QB | 18.26 |
| RB | Derrick Henry RB | 34.60 |
| RB | Austin Ekeler RB | 7.50 |
| WR | Julio Jones WR | 7.40 |
| WR | Amon-Ra St. Brown WR | 7.10 |
| TE | Travis Kelce TE | 13.90 |
| FLEX | Jamaal Williams RB | 1.40 |
| FLEX | Darrell Henderson RB | 23.70 |
| DST | Arizona Cardinals DST | 14.00 |
| Total | 127.86 | |
| Starters | ||
| Pos | Player | Points |
| QB | Justin Herbert QB | 11.00 |
| RB | Marlon Mack RB | 1.20 |
| RB | Joshua Kelley RB | 0.70 |
| WR | Robby Anderson WR | 8.60 |
| WR | Jalen Reagor WR | 0.00 |
| TE | Eric Ebron TE | 8.10 |
| FLEX | Tyler Boyd WR | 1.20 |
| FLEX | Brandin Cooks WR | 13.40 |
| DST | Denver Broncos DST | -2.00 |
| Total | 42.2 | |
| Bench | ||
| Pos | Player | Points |
| BN | Cole Beasley WR | 18.30 |
| BN | Los Angeles Chargers DST | 6.00 |
| BN | Ryan Tannehill QB | 10.94 |
| BN | Chase Edmonds RB | 6.50 |
| BN | Mike Gesicki TE | 15.50 |
| BN | Dallas Goedert TE | 0.00 |
| BN | Allen Lazard WR | 10.20 |
| BN | Mecole Hardman WR | 9.60 |
| BN | Cam Akers RB | 0.00 |
| Bench | ||
| Pos | Player | Points |
| BN | Sammy Watkins WR | 0.00 |
| BN | JuJu Smith-Schuster WR | 0.00 |
| BN | Antonio Gandy-Golden TE | 0.00 |
| BN | Clyde Edwards-Helaire RB | 0.00 |
| BN | Kyle Pitts TE | 0.00 |
| BN | Javian Hawkins RB | 0.00 |
| BN | Jermar Jefferson RB | 0.00 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Teddy Bridgewater QB | 18.26 | 100% |
| RB | Derrick Henry RB | 34.60 | 72.2% |
| RB | Darrell Henderson RB | 23.70 | |
| WR | Cole Beasley WR | 18.30 | 50.9% |
| WR | Allen Lazard WR | 10.20 | |
| TE | Mike Gesicki TE | 15.50 | 89.7% |
| FLEX | Travis Kelce TE | 13.90 | 106.8% |
| FLEX | Mecole Hardman WR | 9.60 | |
| DST | Arizona Cardinals DST | 14.00 | 100% |
| Total | 158.06 | 80.9% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Justin Herbert QB | 11.00 | 100% |
| RB | Marlon Mack RB | 1.20 | 100% |
| RB | Joshua Kelley RB | 0.70 | |
| WR | A.J. Green WR | 16.40 | 28.9% |
| WR | Brandin Cooks WR | 13.40 | |
| TE | Eric Ebron TE | 8.10 | 100% |
| FLEX | Robby Anderson WR | 8.60 | 149% |
| FLEX | Tyler Boyd WR | 1.20 | |
| DST | Denver Broncos DST | -2.00 | -- |
| Total | 58.6 | 72% | |