| Starters | ||
| Pos | Player | Points |
| QB | Kyler Murray QB | 25.44 |
| RB | Sony Michel RB | 0.40 |
| RB | Michael Carter RB | 12.40 |
| WR | Odell Beckham WR | 3.30 |
| WR | Mike Evans WR | 28.60 |
| TE | Jonnu Smith TE | 6.70 |
| FLEX | Ronald Jones II RB | 4.30 |
| FLEX | Christian Kirk WR | 13.00 |
| DST | New England Patriots DST | 13.00 |
| Total | 107.14 | |
| Starters | ||
| Pos | Player | Points |
| QB | Justin Herbert QB | 0.00 |
| RB | Marlon Mack RB | 0.40 |
| RB | Javian Hawkins RB | 0.00 |
| WR | Robby Anderson WR | 2.90 |
| WR | Jalen Reagor WR | 12.25 |
| TE | Kyle Pitts TE | 19.80 |
| FLEX | Tyler Boyd WR | 5.90 |
| FLEX | Brandin Cooks WR | 4.60 |
| DST | Denver Broncos DST | 3.00 |
| Total | 48.85 | |
| Bench | ||
| Pos | Player | Points |
| BN | Tom Brady QB | 32.44 |
| BN | Jacksonville Jaguars DST | 0.00 |
| BN | Todd Gurley RB | 0.00 |
| BN | Dalvin Cook RB | 0.00 |
| BN | Hayden Hurst TE | 5.00 |
| BN | Benny Snell Jr. RB | 0.00 |
| BN | Alexander Mattison RB | 0.00 |
| BN | K.J. Hamler WR | 0.00 |
| Bench | ||
| Pos | Player | Points |
| BN | Eric Ebron TE | 0.00 |
| BN | A.J. Green WR | 8.10 |
| BN | Sammy Watkins WR | 0.00 |
| BN | Derrius Guice RB | 0.00 |
| BN | Antonio Gandy-Golden TE | 0.00 |
| BN | Joshua Kelley RB | 0.00 |
| BN | Quintez Cephus WR | 0.00 |
| BN | Jermar Jefferson RB | 0.00 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Tom Brady QB | 32.44 | 78.4% |
| RB | Michael Carter RB | 12.40 | 76.6% |
| RB | Ronald Jones II RB | 4.30 | |
| WR | Mike Evans WR | 28.60 | 76.7% |
| WR | Christian Kirk WR | 13.00 | |
| TE | Jonnu Smith TE | 6.70 | 100% |
| FLEX | Hayden Hurst TE | 5.00 | 196.6% |
| FLEX | Nico Collins WR | 3.80 | |
| DST | New England Patriots DST | 13.00 | 100% |
| Total | 119.24 | 89.9% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Jared Goff QB | 9.02 | 0% |
| RB | Marlon Mack RB | 0.40 | 100% |
| RB | Jermar Jefferson RB | 0.00 | |
| WR | Jalen Reagor WR | 12.25 | 74.4% |
| WR | A.J. Green WR | 8.10 | |
| TE | Kyle Pitts TE | 19.80 | 100% |
| FLEX | Tyler Boyd WR | 5.90 | 100% |
| FLEX | Brandin Cooks WR | 4.60 | |
| DST | Denver Broncos DST | 3.00 | 100% |
| Total | 63.07 | 77.5% | |