| Starters | ||
| Pos | Player | Points |
| QB | Joe Burrow QB | 11.02 |
| RB | Myles Gaskin RB | 17.10 |
| RB | A.J. Dillon RB | 12.70 |
| WR | Corey Davis WR | 5.00 |
| WR | Jaylen Waddle WR | 17.40 |
| TE | Darren Waller TE | 15.10 |
| FLEX | Damien Harris RB | 7.00 |
| FLEX | Darnell Mooney WR | 20.60 |
| DST | Carolina Panthers DST | 4.00 |
| Total | 109.92 | |
| Starters | ||
| Pos | Player | Points |
| QB | Justin Herbert QB | 38.28 |
| RB | Melvin Gordon RB | 0.00 |
| RB | Joshua Kelley RB | 0.00 |
| WR | Robby Anderson WR | 5.50 |
| WR | Jalen Reagor WR | 5.10 |
| TE | Kyle Pitts TE | 4.40 |
| FLEX | A.J. Green WR | 9.80 |
| FLEX | Jermar Jefferson RB | 0.00 |
| DST | Denver Broncos DST | 0.00 |
| Total | 63.08 | |
| Bench | ||
| Pos | Player | Points |
| BN | Philadelphia Eagles DST | 11.00 |
| BN | Michael Thomas WR | 0.00 |
| BN | Dallas Cowboys DST | 6.00 |
| BN | Damien Williams RB | 0.00 |
| BN | Ty Johnson RB | 1.80 |
| BN | Noah Fant TE | 0.00 |
| BN | Van Jefferson WR | 0.00 |
| BN | Trevor Lawrence QB | 8.62 |
| Bench | ||
| Pos | Player | Points |
| BN | Eric Ebron TE | 9.90 |
| BN | Tyler Boyd WR | 9.30 |
| BN | Sammy Watkins WR | 6.30 |
| BN | Brandin Cooks WR | 2.80 |
| BN | Marlon Mack RB | 0.00 |
| BN | Derrius Guice RB | 0.00 |
| BN | Antonio Gandy-Golden TE | 0.00 |
| BN | Quintez Cephus WR | 0.00 |
| BN | Javian Hawkins RB | 0.00 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Joe Burrow QB | 11.02 | 100% |
| RB | Myles Gaskin RB | 17.10 | 100% |
| RB | A.J. Dillon RB | 12.70 | |
| WR | Darnell Mooney WR | 20.60 | 58.9% |
| WR | Jaylen Waddle WR | 17.40 | |
| TE | Darren Waller TE | 15.10 | 100% |
| FLEX | Rondale Moore WR | 12.95 | 138.3% |
| FLEX | Damien Harris RB | 7.00 | |
| DST | Philadelphia Eagles DST | 11.00 | 36.4% |
| Total | 124.87 | 88% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Justin Herbert QB | 38.28 | 100% |
| RB | Clyde Edwards-Helaire RB | 14.60 | 0% |
| RB | Kerryon Johnson RB | 0.00 | |
| WR | A.J. Green WR | 9.80 | 55.5% |
| WR | Tyler Boyd WR | 9.30 | |
| TE | Eric Ebron TE | 9.90 | 44.4% |
| FLEX | Sammy Watkins WR | 6.30 | 83.1% |
| FLEX | Robby Anderson WR | 5.50 | |
| DST | Denver Broncos DST | 0.00 | -- |
| Total | 93.68 | 67.3% | |