| Starters | ||
| Pos | Player | Points |
| QB | Josh Allen QB | 16.16 |
| RB | Leonard Fournette RB | 10.40 |
| RB | Christian McCaffrey RB | 21.40 |
| WR | Davante Adams WR | 27.00 |
| WR | Keenan Allen WR | 15.70 |
| TE | Dalton Schultz TE | 8.30 |
| FLEX | Marvin Jones WR | 7.20 |
| FLEX | Antonio Gibson RB | 7.50 |
| DST | Seattle Seahawks DST | -1.00 |
| Total | 112.66 | |
| Starters | ||
| Pos | Player | Points |
| QB | Baker Mayfield QB | 5.94 |
| RB | Zack Moss RB | 0.50 |
| RB | Jonathan Taylor RB | 51.90 |
| WR | Justin Jefferson WR | 33.20 |
| WR | DeVonta Smith WR | 8.10 |
| TE | Hunter Henry TE | 3.50 |
| FLEX | Kenyan Drake RB | 5.95 |
| FLEX | Deonte Harris WR | 6.60 |
| DST | San Francisco 49ers DST | 12.00 |
| Total | 127.69 | |
| Bench | ||
| Pos | Player | Points |
| BN | Sterling Shepard WR | 0.00 |
| BN | Amari Cooper WR | 0.00 |
| BN | Jamison Crowder WR | 13.40 |
| BN | Cincinnati Bengals DST | 11.00 |
| BN | Kirk Cousins QB | 31.24 |
| BN | Daniel Jones QB | 5.68 |
| BN | Marquez Callaway WR | 9.10 |
| BN | Elijah Mitchell RB | 0.00 |
| Bench | ||
| Pos | Player | Points |
| BN | Robert Woods WR | 0.00 |
| BN | Tevin Coleman RB | 4.75 |
| BN | Latavius Murray RB | 4.30 |
| BN | Green Bay Packers DST | -2.00 |
| BN | New Orleans Saints DST | 3.00 |
| BN | Cole Kmet TE | 1.70 |
| BN | Pat Freiermuth TE | 9.10 |
| BN | Justin Fields QB | 3.46 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Kirk Cousins QB | 31.24 | 51.7% |
| RB | Christian McCaffrey RB | 21.40 | 100% |
| RB | Leonard Fournette RB | 10.40 | |
| WR | Davante Adams WR | 27.00 | 100% |
| WR | Keenan Allen WR | 15.70 | |
| TE | Dalton Schultz TE | 8.30 | 100% |
| FLEX | Jamison Crowder WR | 13.40 | 65.3% |
| FLEX | Marquez Callaway WR | 9.10 | |
| DST | Cincinnati Bengals DST | 11.00 | -9.1% |
| Total | 147.54 | 76.4% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Russell Wilson QB | 8.48 | 70% |
| RB | Jonathan Taylor RB | 51.90 | 90.6% |
| RB | Kenyan Drake RB | 5.95 | |
| WR | Justin Jefferson WR | 33.20 | 100% |
| WR | DeVonta Smith WR | 8.10 | |
| TE | Pat Freiermuth TE | 9.10 | 38.5% |
| FLEX | Deonte Harris WR | 6.60 | 110.6% |
| FLEX | Tevin Coleman RB | 4.75 | |
| DST | San Francisco 49ers DST | 12.00 | 100% |
| Total | 140.08 | 91.2% | |