| Starters | ||
| Pos | Player | Points |
| QB | Josh Allen QB | 33.48 |
| RB | Christian McCaffrey RB | 13.70 |
| RB | Antonio Gibson RB | 16.50 |
| WR | Amari Cooper WR | 3.20 |
| WR | Davante Adams WR | 25.10 |
| WR | Keenan Allen WR | 8.60 |
| TE | Dalton Schultz TE | 9.70 |
| FLEX | Leonard Fournette RB | 14.70 |
| FLEX | Elijah Mitchell RB | 4.10 |
| DST | Cincinnati Bengals DST | 4.00 |
| Total | 133.08 | |
| Starters | ||
| Pos | Player | Points |
| QB | Ryan Tannehill QB | 23.34 |
| RB | Derrick Henry RB | 8.20 |
| RB | Cam Akers RB | 0.00 |
| WR | Russell Gage WR | 2.30 |
| WR | Amon-Ra St. Brown WR | 16.40 |
| WR | Garrett Wilson WR | 7.20 |
| TE | Travis Kelce TE | 22.10 |
| FLEX | Austin Ekeler RB | 9.20 |
| FLEX | Chase Edmonds RB | 8.50 |
| DST | Los Angeles Chargers DST | 12.00 |
| Total | 109.24 | |
| Bench | ||
| Pos | Player | Points |
| BN | DeAndre Hopkins WR | 0.00 |
| BN | Sterling Shepard WR | 14.10 |
| BN | Seattle Seahawks DST | 4.00 |
| BN | Kirk Cousins QB | 23.08 |
| BN | Tampa Bay Buccaneers DST | 12.00 |
| BN | Corey Davis WR | 10.70 |
| BN | Logan Thomas TE | 6.00 |
| BN | Raheem Mostert RB | 4.50 |
| BN | Nyheim Hines RB | 10.10 |
| Bench | ||
| Pos | Player | Points |
| BN | Arizona Cardinals DST | -6.00 |
| BN | Carson Wentz QB | 31.72 |
| BN | Jamaal Williams RB | 15.50 |
| BN | DOnta Foreman RB | 0.50 |
| BN | Dallas Goedert TE | 7.50 |
| BN | Allen Lazard WR | 0.00 |
| BN | Mecole Hardman WR | 9.25 |
| BN | Skyy Moore WR | 6.70 |
| BN | Brian Robinson RB | 0.00 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Josh Allen QB | 33.48 | 100% |
| RB | Antonio Gibson RB | 16.50 | 96.8% |
| RB | Leonard Fournette RB | 14.70 | |
| WR | Davante Adams WR | 25.10 | 91.6% |
| WR | Curtis Samuel WR | 15.20 | |
| TE | Dalton Schultz TE | 9.70 | 100% |
| FLEX | Sterling Shepard WR | 14.10 | 67.6% |
| FLEX | Christian McCaffrey RB | 13.70 | |
| DST | Tampa Bay Buccaneers DST | 12.00 | 33.3% |
| Total | 154.48 | 86.1% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Carson Wentz QB | 31.72 | 73.6% |
| RB | Jamaal Williams RB | 15.50 | 33.2% |
| RB | Austin Ekeler RB | 9.20 | |
| WR | Devin Duvernay WR | 20.25 | 70.7% |
| WR | Amon-Ra St. Brown WR | 16.40 | |
| TE | Travis Kelce TE | 22.10 | 100% |
| FLEX | Taysom Hill TE | 14.80 | 73.6% |
| FLEX | Mecole Hardman WR | 9.25 | |
| DST | Los Angeles Chargers DST | 12.00 | 100% |
| Total | 151.22 | 72.2% | |