| Starters | ||
| Pos | Player | Points |
| QB | Aaron Rodgers QB | 1.70 |
| RB | James Conner RB | 14.00 |
| RB | Rashaad Penny RB | 7.70 |
| WR | Tee Higgins WR | 3.70 |
| WR | Michael Pittman Jr. WR | 22.60 |
| WR | Elijah Moore WR | 7.40 |
| TE | Tyler Higbee TE | 6.40 |
| FLEX | Tyler Lockett WR | 4.30 |
| FLEX | Adam Thielen WR | 5.10 |
| DST | Buffalo Bills DST | 18.00 |
| Total | 90.9 | |
| Starters | ||
| Pos | Player | Points |
| QB | Jalen Hurts QB | 24.72 |
| RB | Ezekiel Elliott RB | 5.40 |
| RB | Mike Davis RB | 1.10 |
| WR | Stefon Diggs WR | 22.20 |
| WR | Cooper Kupp WR | 25.30 |
| WR | Deebo Samuel WR | 11.60 |
| TE | Mark Andrews TE | 7.70 |
| FLEX | Jakobi Meyers WR | 8.20 |
| FLEX | Miles Sanders RB | 17.50 |
| DST | New Orleans Saints DST | 3.00 |
| Total | 126.72 | |
| Bench | ||
| Pos | Player | Points |
| BN | Matt Ryan QB | 15.28 |
| BN | Jerick McKinnon RB | 6.40 |
| BN | Jamison Crowder WR | 5.30 |
| BN | Robby Anderson WR | 18.70 |
| BN | Samaje Perine RB | 5.20 |
| BN | Tyler Conklin TE | 9.60 |
| BN | Darrel Williams RB | 0.00 |
| BN | Kenny Pickett QB | 0.00 |
| BN | Isaih Pacheco RB | 13.30 |
| Bench | ||
| Pos | Player | Points |
| BN | Will Fuller WR | 0.00 |
| BN | DeVante Parker WR | 1.40 |
| BN | Matthew Stafford QB | 3.80 |
| BN | Indianapolis Colts DST | 7.00 |
| BN | David Njoku TE | 1.20 |
| BN | Calvin Ridley WR | 0.00 |
| BN | Gus Edwards RB | 0.00 |
| BN | Rhamondre Stevenson RB | 3.70 |
| BN | Kenneth Gainwell RB | 10.20 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Matt Ryan QB | 15.28 | 11.1% |
| RB | James Conner RB | 14.00 | 79.5% |
| RB | Isaih Pacheco RB | 13.30 | |
| WR | Michael Pittman Jr. WR | 22.60 | 81.6% |
| WR | Robby Anderson WR | 18.70 | |
| TE | Tyler Conklin TE | 9.60 | 66.7% |
| FLEX | Rashaad Penny RB | 7.70 | 62.3% |
| FLEX | Elijah Moore WR | 7.40 | |
| DST | Buffalo Bills DST | 18.00 | 100% |
| Total | 126.58 | 71.8% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Jalen Hurts QB | 24.72 | 100% |
| RB | Miles Sanders RB | 17.50 | 23.5% |
| RB | Kenneth Gainwell RB | 10.20 | |
| WR | Cooper Kupp WR | 25.30 | 124.4% |
| WR | Stefon Diggs WR | 22.20 | |
| TE | Mark Andrews TE | 7.70 | 100% |
| FLEX | Deebo Samuel WR | 11.60 | 124.8% |
| FLEX | Donovan Peoples-Jones WR | 9.00 | |
| DST | Indianapolis Colts DST | 7.00 | 42.9% |
| Total | 135.22 | 93.7% | |