| Starters | ||
| Pos | Player | Points |
| QB | Josh Allen QB | 23.52 |
| RB | Christian McCaffrey RB | 21.30 |
| RB | Antonio Gibson RB | 7.80 |
| WR | Amari Cooper WR | 1.40 |
| WR | Davante Adams WR | 15.00 |
| WR | Curtis Samuel WR | 5.80 |
| TE | Dalton Schultz TE | 0.00 |
| FLEX | Leonard Fournette RB | 14.90 |
| FLEX | Nyheim Hines RB | 2.30 |
| DST | Cincinnati Bengals DST | 7.00 |
| Total | 99.02 | |
| Starters | ||
| Pos | Player | Points |
| QB | Aaron Rodgers QB | 18.14 |
| RB | James Conner RB | 9.20 |
| RB | Rashaad Penny RB | 28.20 |
| WR | Adam Thielen WR | 11.20 |
| WR | Tee Higgins WR | 21.90 |
| WR | Elijah Moore WR | 7.00 |
| TE | Tyler Higbee TE | 12.30 |
| FLEX | Tyler Lockett WR | 10.45 |
| FLEX | Michael Pittman Jr. WR | 4.60 |
| DST | Buffalo Bills DST | 8.00 |
| Total | 130.99 | |
| Bench | ||
| Pos | Player | Points |
| BN | Marcus Mariota QB | 1.86 |
| BN | DeAndre Hopkins WR | 0.00 |
| BN | Keenan Allen WR | 0.00 |
| BN | Seattle Seahawks DST | 2.00 |
| BN | Kirk Cousins QB | 12.92 |
| BN | Tampa Bay Buccaneers DST | -1.00 |
| BN | Corey Davis WR | 15.90 |
| BN | Logan Thomas TE | 4.40 |
| BN | Raheem Mostert RB | 11.20 |
| Bench | ||
| Pos | Player | Points |
| BN | Matt Ryan QB | 19.84 |
| BN | Jerick McKinnon RB | 0.50 |
| BN | Jamison Crowder WR | 1.55 |
| BN | Rex Burkhead RB | 12.40 |
| BN | Robby Anderson WR | 4.10 |
| BN | Samaje Perine RB | 0.00 |
| BN | Hayden Hurst TE | 10.20 |
| BN | Darrel Williams RB | 1.90 |
| BN | Chuba Hubbard RB | 1.45 |
| BN | Isaih Pacheco RB | 10.85 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Josh Allen QB | 23.52 | 100% |
| RB | Christian McCaffrey RB | 21.30 | 80.4% |
| RB | Leonard Fournette RB | 14.90 | |
| WR | Corey Davis WR | 15.90 | 71.8% |
| WR | Davante Adams WR | 15.00 | |
| TE | Logan Thomas TE | 4.40 | 0% |
| FLEX | Raheem Mostert RB | 11.20 | 90.5% |
| FLEX | Antonio Gibson RB | 7.80 | |
| DST | Cincinnati Bengals DST | 7.00 | 100% |
| Total | 121.02 | 81.8% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Matt Ryan QB | 19.84 | 91.4% |
| RB | Rashaad Penny RB | 28.20 | 92.1% |
| RB | Rex Burkhead RB | 12.40 | |
| WR | Tee Higgins WR | 21.90 | 121.1% |
| WR | Adam Thielen WR | 11.20 | |
| TE | Tyler Higbee TE | 12.30 | 100% |
| FLEX | Isaih Pacheco RB | 10.85 | 70.7% |
| FLEX | Tyler Lockett WR | 10.45 | |
| DST | Buffalo Bills DST | 8.00 | 100% |
| Total | 135.14 | 96.9% | |